The cognitive subscale of the Alzheimer's Disease Assessment Scale in a Brazilian sample

dc.contributor.authorSchultz, Rodrigo Rizek [UNIFESP]
dc.contributor.authorSiviero, Marilena Occhini [UNIFESP]
dc.contributor.authorBertolucci, Paulo Henrique Ferreira [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:29:31Z
dc.date.available2015-06-14T13:29:31Z
dc.date.issued2001-10-01
dc.description.abstractThe cognitive subscale of the Alzheimer's Disease Assessment Scale (ADAS-Cog) is widely used for the evaluation of dementia and is very popular in dementia drug trials because of the characteristics of the scale. The objective of the present study was to adapt the ADAS-Cog for use for the Brazilian population. A major problem is that education is variable, a fact that may influence performance in cognitive evaluation. This study was conducted on a control group (CG) of 96 subjects (25 males and 71 females aged 68 ± 8.6 years) and on 44 Alzheimer's disease (AD) patients (19 males and 25 females aged 72 ± 6.4 years) with mild dementia (Clinical Dementia Rating score 1). For statistical analysis groups were divided into three educational levels: I, 0-4 years of schooling (65 CG/20 AD); II, 5-11 years of schooling (19 CG/7 AD), and III, 12 or more years of schooling (12 CG/17 AD). The battery was applied according to original instructions. Total mean score for CG and AD was 10.9 and 22.9 for level I, 7.8 and 22.4 for level II, and 6.2 and 15.4 for level III, respectively. These results indicate that our version of the ADAS-Cog is useful to identify mild dementia, though there may be an overlapping when comparing high education demented with low education non-demented subjects.en
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Neurologia e Neurocirurgia
dc.description.affiliationUnifespUNIFESP, EPM, Depto. de Neurologia e Neurocirurgia
dc.description.sourceSciELO
dc.format.extent1295-1302
dc.identifierhttp://dx.doi.org/10.1590/S0100-879X2001001000009
dc.identifier.citationBrazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 34, n. 10, p. 1295-1302, 2001.
dc.identifier.doi10.1590/S0100-879X2001001000009
dc.identifier.fileS0100-879X2001001000009.pdf
dc.identifier.issn0100-879X
dc.identifier.scieloS0100-879X2001001000009
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/1266
dc.identifier.wosWOS:000171856300009
dc.language.isoeng
dc.publisherAssociação Brasileira de Divulgação Científica
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.rightsAcesso aberto
dc.subjectdementiaen
dc.subjectAlzheimer's diseaseen
dc.subjectneuropsychological evaluationen
dc.subjecteducationen
dc.titleThe cognitive subscale of the Alzheimer's Disease Assessment Scale in a Brazilian sampleen
dc.typeArtigo
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