Application of computed tomography images in the evaluation of magnetic nanoparticles biodistribution

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dc.contributor.authorDias, Argleydson Leao
dc.contributor.authorKunzel, Roseli
dc.contributor.authorLevenhagen, Ronaldo Savarino [UNIFESP]
dc.contributor.authorOkuno, Emico
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionCtr Univ Franciscano
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:05:17Z
dc.date.available2016-01-24T14:05:17Z
dc.date.issued2010-08-01
dc.description.abstractIn this work we evaluate the effectiveness of computed tomography images as a tool to determine magnetic nanoparticle biodistribution over biological tissues. for this purpose, tomography images for magnetic nanoparticles, composed of Fe(3)O(4), coated with 2,3-dimercaptosuccinic acid (DMSA), were generated at several material concentrations. the comparison of CT numbers, calculated from these images generated at clinical conditions, with typical CT numbers for biological tissues, shows that the detection of nanoparticle in most tissues is only possible for high material concentrations. (C) 2010 Elsevier B.V. All rights reserved.en
dc.description.affiliationUniv São Paulo, Inst Fis, BR-05508900 São Paulo, Brazil
dc.description.affiliationCtr Univ Franciscano, Area Ciencias Tecnol, BR-97010032 Santa Maria, RS, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, BR-09941510 Diadema, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, BR-09941510 Diadema, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIDCNPq: 150219/2009-1
dc.description.sponsorshipIDCNPq: 307095/2008-8
dc.format.extent2405-2407
dc.identifierhttp://dx.doi.org/10.1016/j.jmmm.2010.02.046
dc.identifier.citationJournal of Magnetism and Magnetic Materials. Amsterdam: Elsevier B.V., v. 322, n. 16, p. 2405-2407, 2010.
dc.identifier.doi10.1016/j.jmmm.2010.02.046
dc.identifier.issn0304-8853
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/32782
dc.identifier.wosWOS:000277316100020
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofJournal of Magnetism and Magnetic Materials
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectMagnetic nanoparticleen
dc.subjectComputed tomographyen
dc.subjectImaging contrasten
dc.subjectIodineen
dc.titleApplication of computed tomography images in the evaluation of magnetic nanoparticles biodistributionen
dc.typeinfo:eu-repo/semantics/article
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