The Effects of 660nm and 780nm Laser Irradiation on Viability of Random Skin Flap in Rats

dc.contributor.authorCury, Vivian
dc.contributor.authorBossini, Paulo Sergio
dc.contributor.authorFangel, Renan
dc.contributor.authorCrusca, Jaqueline de Sousa
dc.contributor.authorRenno, Ana Claudia Muniz [UNIFESP]
dc.contributor.authorParizotto, Nivaldo Antonio
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.abstractBackground and Objective: Some studies have shown that laser phototherapy is able to increase skin flap viability by decreasing the necrotic area and increasing neoangiogenesis. However, the mechanism by which laser acts on cells is not fully understood. the present study investigated the effects of two different laser wavelengths at 30 and 40 J/cm(2) on the viability of skin flap in rats. Material and Methods: Sixty male animals were used in this study. They were distributed into the following groups (n = 12 each group): control group, group irradiated with 660nm at 30 J/cm(2); group irradiated with 780 nm, at 30 J/cm(2), group irradiated with 660nm at 40 J/cm(2); and group irradiated with 780nm at 40 J/cm(2). the skin flap was performed on the back of all animals studied, with a plastic sheet interposed between the flap and the donor site. Laser irradiation was done immediately after the surgery and on days 1, 2, 3, and 4 post-surgery. the percentage of the necrotic area of the flap was calculated at day 7 post-surgery. Results: Control group showed a necrotic area of 62.83%. Interestingly, no statistically significant differences were found among the treated groups and the control group. Conclusion: This present study showed that 660nm and 780nm lasers at doses of 30 and 40 J/cm(2) were not effective for decreasing the necrotic area of the skin flaps in rats.en
dc.description.affiliationUniv Fed Sao Carlos, Dept Physiotherapy, BR-13560 Sao Carlos, SP, Brazil
dc.description.affiliationUniv São Paulo, Dept Bioengn, Sao Carlos, SP, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Biosci, BR-15011000 Santos, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Biosci, BR-15011000 Santos, SP, Brazil
dc.description.sourceWeb of Science
dc.identifier.citationPhotomedicine and Laser Surgery. New Rochelle: Mary Ann Liebert Inc, v. 27, n. 5, p. 721-724, 2009.
dc.publisherMary Ann Liebert Inc
dc.relation.ispartofPhotomedicine and Laser Surgery
dc.rightsAcesso restrito
dc.titleThe Effects of 660nm and 780nm Laser Irradiation on Viability of Random Skin Flap in Ratsen