Assessment of aerobic capacity during swimming exercise in ob/ob mice

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dc.contributor.authorAlmeida, W. S.
dc.contributor.authorLima, L. C. J.
dc.contributor.authorCunha, V. N. C.
dc.contributor.authorCunha, R. R.
dc.contributor.authorAraujo, R. C.
dc.contributor.authorBarros, C. C. [UNIFESP]
dc.contributor.authorSimoes, H. G.
dc.contributor.authorCampbell, C. S. G.
dc.contributor.institutionUniv Catolica Brasilia
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:17:29Z
dc.date.available2016-01-24T14:17:29Z
dc.date.issued2011-12-01
dc.description.abstractObesity is a highly prevalent condition associated with several diseases. Physical exercise has been considered as a non-pharmacological tool in the treatment of obesity. However, several aspects underlying exercise evaluation and prescription in obesity and associated pathologies are still under investigation. Although many research involving exercise have been performed in animal models, there is a lack of protocols for aerobic capacity assessment in obese animals, such as the ob/ob mice. This study aimed the following: (i) to verify the possibility of determining the lactate threshold (LT) on swimming exercise in ob/ob mice and in non-obese heterozygote mice (ob/OB), through visual inspection (vLT) and polynomial adjustment (pLT); and (ii) to verify if the LT determined through these protocols corresponds to the maximal lactate steady state (MLSS). Eight ob/ob and ten ob/OB mice performed an incremental exercise test to determine vLT and pLT as well as constant-load exercise bouts to determine MLSS. There were no within-group differences between vLT, pLT and MLSS [ob/ob: similar to 5.3% body weight (BW); ob/OB: similar to 3 center dot 6%BW] with a high agreement among protocols. in conclusion, the identification of the LT and MLSS intensities was possible for both groups. These data suggest that the proposed protocols may be used in new research on the effects of different exercise intensities on some aspects of obesity. Copyright (c) 2011 John Wiley & Sons, Ltd.en
dc.description.affiliationUniv Catolica Brasilia, Programa Mestrado & Doutorado Educ Fis, BR-71966900 Taguatinga, DF, Brazil
dc.description.affiliationUniv Catolica Brasilia, Univ Brasilia UNB, Programa Mestrado Educ Fis, BR-71966900 Taguatinga, DF, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Med, Div Nefrol, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Biofis, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Med, Div Nefrol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Biofis, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIDCAPES: 0216054
dc.format.extent666-672
dc.identifierhttp://dx.doi.org/10.1002/cbf.1803
dc.identifier.citationCell Biochemistry and Function. Malden: Wiley-Blackwell, v. 29, n. 8, p. 666-672, 2011.
dc.identifier.doi10.1002/cbf.1803
dc.identifier.issn0263-6484
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34265
dc.identifier.wosWOS:000297632400007
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofCell Biochemistry and Function
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.subjectaerobic exerciseen
dc.subjectlactate thresholden
dc.subjectleptinen
dc.subjectmaximal lactate steady stateen
dc.subjectmiceen
dc.titleAssessment of aerobic capacity during swimming exercise in ob/ob miceen
dc.typeinfo:eu-repo/semantics/article
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