The influence of hemorrhagic shock on ventilation through needle cricothyroidotomy in pigs

dc.contributor.authorMurad, Ivan [UNIFESP]
dc.contributor.authorAbib, Simone de Campos Vieira [UNIFESP]
dc.contributor.authorLima, Daniela P. A. [UNIFESP]
dc.contributor.authorFerreira, Paulo S. V. S. [UNIFESP]
dc.contributor.authorSantos, Eduardo Q. dos
dc.contributor.authorBataglia, Thomas V.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade Estadual de Maringá (UEM)
dc.date.accessioned2016-01-24T14:27:57Z
dc.date.available2016-01-24T14:27:57Z
dc.date.issued2012-11-01
dc.description.abstractBackground: the aim of this study was to examine the effects of controlled hemorrhage and shock on oxygenation and ventilation using needle cricothyroidotomy and jet ventilation in an animal model.Methods: Twenty-four male pigs were randomly allocated into 4 groups: SHOCK (animals in hemorrhagic shock only), CRICH (animals that underwent needle cricothyroidotomy only), SHOCK+ CRICH (animals in hemorrhagic shock + needle cricothyroidotomy), and SHAM (anesthetized animals submitted to surgical preparation only). All animals were surgically prepared and were observed for a period of 40 minutes (T0 - T40). Hemodynamic and blood gas variables were compared using analysis of variance and Bonferroni post hoc testing at a level of significance of 95%.Results: CRICH and SHOCK+ CRICH developed respiratory acidosis, with a progressive decrease of arterial pH after T20, and they presented a significant increase of PaCO2 levels after T10, when compared with SHAM and SHOCK (P < .001). When SHOCK+ CRICH was compared with CRICH, it presented a larger increase of PaCO2 after T10 (P = .036) and an even more significant increase after T20 (P = .009).Conclusion: Hemorrhagic shock anticipated and intensified the retention of carbon dioxide and respiratory acidosis during manual jet ventilation through needle cricothyroidotomy in comparison with animals with jet ventilation but without shock. the results found in this work should be considered in future protocols for the assistance of victims of trauma in prehospital settings. (C) 2012 Elsevier Inc. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Paulista Sch Med, Dept Surg, São Paulo, Brazil
dc.description.affiliationUniv Estadual Maringa, Dept Med, Maringa, Parana, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Paulista Sch Med, Dept Surg, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1684-1690
dc.identifierhttp://dx.doi.org/10.1016/j.ajem.2012.01.017
dc.identifier.citationAmerican Journal of Emergency Medicine. Philadelphia: W B Saunders Co-Elsevier Inc, v. 30, n. 9, p. 1684-1690, 2012.
dc.identifier.doi10.1016/j.ajem.2012.01.017
dc.identifier.issn0735-6757
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/35454
dc.identifier.wosWOS:000311997600004
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofAmerican Journal of Emergency Medicine
dc.rightsAcesso restrito
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.titleThe influence of hemorrhagic shock on ventilation through needle cricothyroidotomy in pigsen
dc.typeArtigo
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