Infections with human coronaviruses NL63 and OC43 among hospitalised and outpatient individuals in São Paulo, Brazil

dc.contributor.authorCabeça, Tatiane Karen [UNIFESP]
dc.contributor.authorCarraro, Emerson [UNIFESP]
dc.contributor.authorWatanabe, Aripuanã Sakurada Aranha [UNIFESP]
dc.contributor.authorGranato, Celso Francisco Hernandes [UNIFESP]
dc.contributor.authorBellei, Nancy Cristina Junqueira [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:44:51Z
dc.date.available2015-06-14T13:44:51Z
dc.date.issued2012-08-01
dc.description.abstractThe incidence and clinical features of human coronaviruses (HCoVs) among Brazilian patients with respiratory illness are not well known. We investigated the prevalence of HCoVs among Brazilian outpatients and hospitalised patients with respiratory illnesses during 2009 and 2010. To identify the HCoVs, pancoronavirus and species-specific reverse-transcriptase polymerase chain reaction assays were performed. Five of 394 samples were positive for HCoVs (1.2%): 1/182 (0.5%) outpatients and 4/212 (1.8%) hospitalised patients. The OC43 and NL63 HCoVs were identified. Two patients were admitted to the intensive care unit. Underlying chronic disease was reported in cases and one diabetic adult died. HCoVs can cause lower respiratory infections and hospitalisation. Patients with pre-existing conditions and respiratory infections should be evaluated for HCoV infections.en
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Departamento de Medicina Laboratório de Virologia Clínica
dc.description.affiliationUnifespUNIFESP, Depto. de Medicina Laboratório de Virologia Clínica
dc.description.sourceSciELO
dc.format.extent693-694
dc.identifierhttp://dx.doi.org/10.1590/S0074-02762012000500020
dc.identifier.citationMemórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 107, n. 5, p. 693-694, 2012.
dc.identifier.doi10.1590/S0074-02762012000500020
dc.identifier.fileS0074-02762012000500020.pdf
dc.identifier.issn0074-0276
dc.identifier.scieloS0074-02762012000500020
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/7213
dc.identifier.wosWOS:000306973400020
dc.language.isoeng
dc.publisherInstituto Oswaldo Cruz, Ministério da Saúde
dc.relation.ispartofMemórias do Instituto Oswaldo Cruz
dc.rightsAcesso aberto
dc.subjecthuman coronavirus OC43en
dc.subjecthuman coronavirus NL63en
dc.subjectrespiratory tract infectionsen
dc.titleInfections with human coronaviruses NL63 and OC43 among hospitalised and outpatient individuals in São Paulo, Brazilen
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