Results of a randomized controlled trial to assess the effects of a mobile SMS-based intervention on treatment adherence in HIV/AIDS-infected Brazilian women and impressions and satisfaction with respect to incoming messages

dc.contributor.authorCosta, Thiago Martini da [UNIFESP]
dc.contributor.authorPeres Barbosa, Barbara Jaqueline [UNIFESP]
dc.contributor.authorGomes e Costa, Durval Alex [UNIFESP]
dc.contributor.authorSigulem, Daniel
dc.contributor.authorMarin, Heimar de Fatima
dc.contributor.authorCastelo Filho, Adauto [UNIFESP]
dc.contributor.authorPisa, Ivan Torres
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:27:04Z
dc.date.available2016-01-24T14:27:04Z
dc.date.issued2012-04-01
dc.description.abstractObjective: To assess whether a warning system based on mobile SMS messages increases the adherence of HIV-infected Brazilian women to antiretroviral drug-based treatment regimens and their impressions and satisfaction with respect to incoming messages.Design: A randomized controlled trial was conducted from May 2009 to April 2010 with HIV-infected Brazilian women. All participants (n = 21) had a monthly multidisciplinary attendance; each participant was followed over a 4-month period, when adherence measures were obtained. Participants in the intervention group (n = 8) received SMS messages 30 min before their last scheduled time for a dose of medicine during the day. the messages were sent every Saturday and Sunday and on alternate days during the working week. Participants in the control group (n = 13) did not receive messages.Measurements: Self-reported adherence, pill counting, microelectronic monitors (MEMS) and an interview about the impressions and satisfaction with respect to incoming messages.Results: the HIV Alert System (HIVAS) was developed over 7 months during 2008 and 2009. After the study period, self-reported adherence indicated that 11 participants (84.62%) remained compliant in the control group (adherence exceeding 95%), whereas all 8 participants in the intervention group (100.00%) remained compliant. in contrast, the counting pills method indicated that the number of compliant participants was 5 (38.46%) for the control group and 4 (50.00%) for the intervention group. Microelectronic monitoring indicated that 6 participants in the control group (46.15%) were adherent during the entire 4-month period compared to 6 participants in the intervention group (75.00%). According to the feedback of the 8 participants who completed the research in the intervention group, along with the feedback of 3 patients who received SMS for less than 4 months, that is, did not complete the study, 9 (81.81%) believed that the SMS messages aided them in treatment adherence, and 10 (90.90%) responded that they would like to continue receiving SMS messages. SMS messaging can help Brazilian women living with HIV/AIDS to adhere to antiretroviral therapy for a period of at least 4 months. in general, the results are encouraging because the SMS messages stimulated more participants in the intervention group to be adherent to their treatment, and the patients were satisfied with the messages received, which were seen as reminders, incentives and signs of affection by the health clinic for a marginalized population. (c) 2012 Published by Elsevier Ireland Ltd.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Informat Saude, UNIFESP, Hlth Informat Postgrad Program, BR-04038032 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Infectol Postgrad Program, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Med, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Informat Saude, UNIFESP, Hlth Informat Postgrad Program, BR-04038032 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Infectol Postgrad Program, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Med, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipNIH
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIDNIH: D43TW007015-06 BRIGHT
dc.description.sponsorshipIDCAPES: 0810497
dc.description.sponsorshipIDCNPq: 301735/2009-3
dc.format.extent257-269
dc.identifierhttp://dx.doi.org/10.1016/j.ijmedinf.2011.10.002
dc.identifier.citationInternational Journal of Medical Informatics. Clare: Elsevier B.V., v. 81, n. 4, p. 257-269, 2012.
dc.identifier.doi10.1016/j.ijmedinf.2011.10.002
dc.identifier.issn1386-5056
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34760
dc.identifier.wosWOS:000301378400004
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofInternational Journal of Medical Informatics
dc.rightsAcesso restrito
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectAdherenceen
dc.subjectComplianceen
dc.subjectHIVen
dc.subjectAIDSen
dc.subjectRemindingen
dc.subjectCell phonesen
dc.subjectWireless text messagingen
dc.subjectSMSen
dc.titleResults of a randomized controlled trial to assess the effects of a mobile SMS-based intervention on treatment adherence in HIV/AIDS-infected Brazilian women and impressions and satisfaction with respect to incoming messagesen
dc.typeArtigo
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