Can poor sleep affect skin integrity?

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dc.contributor.authorKahan, V. [UNIFESP]
dc.contributor.authorAndersen, M. L. [UNIFESP]
dc.contributor.authorTomimori, J. [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:05:46Z
dc.date.available2016-01-24T14:05:46Z
dc.date.issued2010-12-01
dc.description.abstractModern society has reported a decline in sleep time in the recent decades. This reduction can increase the morbidity and mortality of several diseases and leads to an immunosuppressive state. the skin is the largest organ in the human body and collagen, its main component, has a key role in the structure and integrity of the organism. the entire sequence of events necessary during collagen formation can be affected by endogenous and exogenous factors. A variety of studies in the literature have shown that sleep plays a role in restoring immune system function and that changes in the immune response may affect collagen production. Several studies of prolonged sleep deprivation suggest a break in skin barrier function and mucous membranes. in fact, the reduction of sleep time affects the composition and integrity of various systems. Thus, we hypothesized that lack of sleep as well as other types of stress can impair skin integrity. (C) 2010 Elsevier B.V. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Psicobiol, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Dermatol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Psicobiol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Dermatol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipAFIP
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent535-537
dc.identifierhttp://dx.doi.org/10.1016/j.mehy.2010.07.018
dc.identifier.citationMedical Hypotheses. Edinburgh: Churchill Livingstone, v. 75, n. 6, p. 535-537, 2010.
dc.identifier.doi10.1016/j.mehy.2010.07.018
dc.identifier.issn0306-9877
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/33131
dc.identifier.wosWOS:000286918300019
dc.language.isoeng
dc.publisherChurchill Livingstone
dc.relation.ispartofMedical Hypotheses
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.titleCan poor sleep affect skin integrity?en
dc.typeinfo:eu-repo/semantics/article
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