IGG AND IGE ANTIBODY-RESPONSES TO DUST-MITE ALLERGENS AMONG CHILDREN WITH ASTHMA IN BRAZIL

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dc.contributor.authorRizzo, M. C.
dc.contributor.authorArruda, Luisa Karla de Paula [UNIFESP]
dc.contributor.authorChapman, M. D.
dc.contributor.authorFernandezcaldas, E.
dc.contributor.authorBaggio, D.
dc.contributor.authorPlattsmills, TAE
dc.contributor.authorNaspitz, Charles Kirov [UNIFESP]
dc.contributor.institutionUNIV VIRGINIA
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUNIV S FLORIDA
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2018-06-15T13:50:12Z
dc.date.available2018-06-15T13:50:12Z
dc.date.issued1993-08-01
dc.description.abstractWe compared exposure and levels of IgE and IgG antibodies to inhalant allergens in 20 children with asthma and positive skin tests to Dermatophagoides pteronyssinus, living in Sao Paulo, to 20 control children without history of asthma or allergy and negative skin tests to D. pteronyssinus, D. farinae, and Blomia tropicalis. In 16/20 and 17/20 houses of asthmatic and control children, respectively, at least one sample was obtained which contained > 10 mug Der p I/g of dust. Serum IgE antibodies to D. pteronyssinus and Blomia tropicalis were > 200 RAST U/mL in 19120 and in 16/20 asthmatic children, respectively. In the control group, IgE antibodies to either mite species were < 40 RAST U/mL in most cases. IgG anti-Der p I and anti-Der f I antibodies were detected in 17/20 asthmatics, as opposed to 3/20 controls. Neither cat nor cockroach allergens caused significant sensitization among asthmatic or control children. Although exposure to high levels of mite allergens was common in Sao Paulo, significant IgE and IgG antibody responses were detected only in children with asthma.en
dc.description.affiliationUNIV VIRGINIA,DIV ALLERGY & CLIN IMMUNOL,BOX 225,CHARLOTTESVILLE,VA 22908
dc.description.affiliationESCOLA PAULISTA MED,SAO PAULO,BRAZIL
dc.description.affiliationUNIV S FLORIDA,TAMPA,FL 33620
dc.description.affiliationUNIV SAO PAULO,SAO PAULO,BRAZIL
dc.description.affiliationUnifespESCOLA PAULISTA MED,SAO PAULO,BRAZIL
dc.description.sourceWeb of Science
dc.format.extent152-158
dc.identifier.citationAnnals Of Allergy. Arlington Hts: Amer Coll Allergy Asthma Immunology, v. 71, n. 2, p. 152-158, 1993.
dc.identifier.issn0003-4738
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/42562
dc.identifier.wosWOS:A1993LT45600014
dc.language.isoeng
dc.publisherAmer Coll Allergy Asthma Immunology
dc.relation.ispartofAnnals Of Allergy
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.titleIGG AND IGE ANTIBODY-RESPONSES TO DUST-MITE ALLERGENS AMONG CHILDREN WITH ASTHMA IN BRAZILen
dc.typeinfo:eu-repo/semantics/article
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