Influence of genotype on dopamine transporter availability in human striatum and sleep architecture

Guindalini, Camila [UNIFESP]; Martins, Raquel Cristina [UNIFESP]; Andersen, Monica L. [UNIFESP]; Tufik, Sergio [UNIFESP]

Influence of genotype on dopamine transporter availability in human striatum and sleep architecture

Data

2010-09-30

Autores

Guindalini, Camila

Martins, Raquel Cristina

Andersen, Monica L.

Tufik, Sergio

Tipo

Artigo

Resumo

Genetic variants may modulate dopamine transporter (DAT) availability in the brain. A polymorphism within the intron 8 of the DAT1 gene was evaluated in 27 healthy men. No correlation between Int8 VNTR and either the inter-individual variability of the sleep architecture, or the DAT availability, as measured by single photon emission computed tomography (SPECT) and [(99m)Tc]TRODAT-1 was observed. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

Citação

Psychiatry Research. Clare: Elsevier B.V., v. 179, n. 2, p. 238-240, 2010.