Violence and post-traumatic stress disorder in São Paulo and Rio de Janeiro, Brazil: the protocol for an epidemiological and genetic survey

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dc.contributor.authorAndreoli, Sergio Baxter [UNIFESP]
dc.contributor.authorRibeiro, Wagner Silva [UNIFESP]
dc.contributor.authorQuintana, Maria Inês [UNIFESP]
dc.contributor.authorGuindalini, Camila [UNIFESP]
dc.contributor.authorBreen, Gerome
dc.contributor.authorBlay, Sergio Luis [UNIFESP]
dc.contributor.authorCoutinho, Evandro S. F.
dc.contributor.authorHarpham, Trudy
dc.contributor.authorJorge, Miguel Roberto [UNIFESP]
dc.contributor.authorLara, Diogo Rizzato
dc.contributor.authorMoriyama, Tais Silveira [UNIFESP]
dc.contributor.authorQuarantini, Lucas de Castro [UNIFESP]
dc.contributor.authorGadelha, Ary [UNIFESP]
dc.contributor.authorVilete, Liliane Maria Pereira
dc.contributor.authorYeh, Mary Sau Ling [UNIFESP]
dc.contributor.authorPrince, Martin
dc.contributor.authorFigueira, Ivan
dc.contributor.authorBressan, Rodrigo Affonseca [UNIFESP]
dc.contributor.authorMello, Marcelo Feijó de [UNIFESP]
dc.contributor.authorDewey, Michael E.
dc.contributor.authorFerri, Cleusa P.
dc.contributor.authorMari, Jair de Jesus [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionKings Coll London
dc.contributor.institutionENSP FIOCRUZ
dc.contributor.institutionLondon S Bank Univ
dc.contributor.institutionLondon Sch Hyg & Trop Med
dc.contributor.institutionPontificia Univ Catolica Rio Grande do Sul
dc.contributor.institutionUniv London
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)
dc.date.accessioned2016-01-24T13:52:38Z
dc.date.available2016-01-24T13:52:38Z
dc.date.issued2009-06-07
dc.description.abstractBackground: violence is a public health major concern, and it is associated with post-traumatic stress disorder and other psychiatric outcomes. Brazil is one of the most violent countries in the world, and has an extreme social inequality. Research on the association between violence and mental health may support public health policy and thus reduce the burden of disease attributable to violence. the main objectives of this project were: to study the association between violence and mental disorders in the Brazilian population; to estimate the prevalence rates of exposure to violence, post-traumatic stress disorder, common metal disorder, and alcohol hazardous use and dependence: and to identify contextual and individual factors, including genetic factors, associated with the outcomes.Methods/design: one phase cross-sectional survey carried out in São Paulo and Rio de Janeiro, Brazil. A multistage probability to size sampling scheme was performed in order to select the participants (3000 and 1500 respectively). the cities were stratified according to homicide rates, and in São Paulo the three most violent strata were oversampled. the measurements included exposure to traumatic events, psychiatric diagnoses (CIDI 2.1), contextual (homicide rates and social indicators), and individual factors, such as demographics, social capital, resilience, help seeking behaviours. the interviews were carried between June/2007 February/2008, by a team of lay interviewers. the statistical analyses will be weight-adjusted in order to take account of the design effects. Standardization will be used in order to compare the results between the two centres. Whole genome association analysis will be performed on the 1 million SNP (single nucleotide polymorphism) arrays, and additional association analysis will be performed on additional phenotypes. the Ethical Committee of the Federal University of São Paulo approved the study, and participants who matched diagnostic criteria have been offered a referral to outpatient clinics at the Federal University of São Paulo and Federal University of Rio de Janeiro.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Psychiat, São Paulo, Brazil
dc.description.affiliationKings Coll London, Inst Psychiat, MRC Social, London WC2R 2LS, England
dc.description.affiliationENSP FIOCRUZ, Rio de Janeiro, Brazil
dc.description.affiliationLondon S Bank Univ, London, England
dc.description.affiliationLondon Sch Hyg & Trop Med, London WC1, England
dc.description.affiliationPontificia Univ Catolica Rio Grande do Sul, Fac Biociencias, Porto Alegre, RS, Brazil
dc.description.affiliationUniv London, Kings Coll, Inst Psychiat, Ctr Publ Mental Hlth,Hlth Serv & Populat Res Dept, London, England
dc.description.affiliationUniv Fed Rio de Janeiro, IPUB, Inst Psychiat, Rio de Janeiro, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Psychiat, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIDFAPESP: 2004/15039-0
dc.description.sponsorshipIDCNPq: 420122/2005-2
dc.format.extent9
dc.identifierhttp://dx.doi.org/10.1186/1471-244X-9-34
dc.identifier.citationBmc Psychiatry. London: Biomed Central Ltd, v. 9, 9 p., 2009.
dc.identifier.doi10.1186/1471-244X-9-34
dc.identifier.fileWOS000268083500002.pdf
dc.identifier.issn1471-244X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/31602
dc.identifier.wosWOS:000268083500002
dc.language.isoeng
dc.publisherBiomed Central Ltd
dc.relation.ispartofBmc Psychiatry
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleViolence and post-traumatic stress disorder in São Paulo and Rio de Janeiro, Brazil: the protocol for an epidemiological and genetic surveyen
dc.typeinfo:eu-repo/semantics/article
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