Sleep disordered breathing in Parkinson's disease: A critical appraisal

dc.contributor.authorSilva-Junior, Francisco P. da
dc.contributor.authorPrado, Gilmar F. do [UNIFESP]
dc.contributor.authorBarbos, Egberto R.
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.authorTogeiro, Sonia M. [UNIFESP]
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:35:34Z
dc.date.available2016-01-24T14:35:34Z
dc.date.issued2014-04-01
dc.description.abstractParkinson's disease (PD) is the second most common neurodegenerative disorder, characterized by resting tremor, rigidity, bradykinesia and postural instability, and is associated with non-motor features, including sleep abnormalities. the high prevalence of excessive daytime sleepiness and snoring in PD patients has led to the suggestion that sleep disordered breathing (SDB) is more common in these individuals than in normal subjects. We aimed to review the literature on SDB prevalence and its clinical repercussions in PD. A PubMed search was performed to identify controlled studies, published from January 1990 through October 2012, which addressed the prevalence of SDB diagnosed by polysomnography in idiopathic PD. From the seven studies included, five reported similar or lower prevalence of SDB in patients when compared to healthy age-matched controls. Two studies reported less oxyhemoglobin desaturation during sleep among patients. These results did not support the idea that PD patients are at increased risk of SDB and indicate that they may not present significant hypoxernia. the prevalence of obstructive sleep apnea syndrome and the long-term outcomes of disordered breathing events during sleep have not been adequately studied in PD. (C) 2013 Elsevier B.V. All rights reserved.en
dc.description.affiliationUniv São Paulo, Dept Neurol, BR-05403000 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Neurol, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Psychobiol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Neurol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Psychobiol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipAssociacao Fundo de Incentivo a Pesquisa (AFIP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent173-178
dc.identifierhttp://dx.doi.org/10.1016/j.smrv.2013.04.005
dc.identifier.citationSleep Medicine Reviews. London: W B Saunders Co Ltd, v. 18, n. 2, p. 173-178, 2014.
dc.identifier.doi10.1016/j.smrv.2013.04.005
dc.identifier.issn1087-0792
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/37631
dc.identifier.wosWOS:000332267000008
dc.language.isoeng
dc.publisherW B Saunders Co Ltd
dc.relation.ispartofSleep Medicine Reviews
dc.rightsAcesso restrito
dc.subjectSleep disordered breathingen
dc.subjectParkinson diseaseen
dc.subjectCardiovascular diseasesen
dc.titleSleep disordered breathing in Parkinson's disease: A critical appraisalen
dc.typeResenha
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