Important Mycoses in Children in South America

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dc.citation.issue1
dc.citation.volume10
dc.contributor.authorCarlesse, Fabianne [UNIFESP]
dc.contributor.authorPaixao de Sousa da Silva, Adriana Maria [UNIFESP]
dc.contributor.authorSantolaya, Maria Elena
dc.coverageNew York
dc.date.accessioned2020-08-21T16:59:57Z
dc.date.available2020-08-21T16:59:57Z
dc.date.issued2016
dc.description.abstractInvasive fungal disease (IFD) is an important infection with high rates of morbidity and mortality in hospitalized patients. Data on incidence, risk factors, and mortality of IFD in the pediatric population, mainly in South America, are scarce. The aim of this paper was to review the literature about the most important IFD in pediatrics in South America. We searched three electronic databases (Medline, Lilacs, and Cochrane databases) for studies published between 2012 and 2015; case reports and editorial were excluded. Twenty-two articles were found on Candida spp. infections; eight on Paracoccidiodes spp.; two on Cryptococcus spp.; and one on Aspergillus spp. Candida albicans was the main agent, followed by Candida parapsilosis in pediatric population. Paracoccidioides spp. had a prevalence ranging from 2.3 to 35.3 % with ages between 11 and 29 years, malnutrition, and hepatic involvement related to the worst prognosis. Cryptococcus spp. showed a prevalence of 2.6 % in under 16 years old, with cryptococcal meningitis most observed, mainly by Cryptococcus neoformans (94.1 %). Aspergillosis and other mold infections, as zygomycosis and fusariosis occurring mostly in immunocompromised children, related with relevant morbidity and mortality in this population.en
dc.description.affiliationUniv Fed Sao Paulo UNIFESP, GRAACC Inst Oncol Pediat, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo UNIFESP, Sao Paulo, Brazil
dc.description.affiliationUniv Chile, Fac Med, Hosp Ninos Dr Luis Calvo Mackenna, Infect Dis Unit,Dept Pediat, Santiago, Chile
dc.description.affiliationUnifespUniv Fed Sao Paulo UNIFESP, GRAACC Inst Oncol Pediat, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo UNIFESP, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent10-23
dc.identifierhttp://dx.doi.org/10.1007/s12281-016-0249-2
dc.identifier.citationCurrent Fungal Infection Reports. New York, v. 10, n. 1, p. 10-23, 2016.
dc.identifier.doi10.1007/s12281-016-0249-2
dc.identifier.fileWOS000382381000003.pdf
dc.identifier.issn1936-3761
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57809
dc.identifier.wosWOS:000382381000003
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofCurrent Fungal Infection Reports
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMycosesen
dc.subjectChildrenen
dc.subjectSouth Americaen
dc.subjectFungal infectionen
dc.subjectPediatric fungal infectionsen
dc.titleImportant Mycoses in Children in South Americaen
dc.typeinfo:eu-repo/semantics/article
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