Efeito agudo e crônico da suplementação de bebida energética nos parâmetros cardiovasculares de ratos SHR submetidos ao teste de esforço máximo
Arquivos
Data
2013-02-18
Autores
Carvalho, Francine Pereira de 
Orientadores
Medeiros, Alessandra
Tipo
Trabalho de conclusão de curso
Título da Revista
ISSN da Revista
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Resumo
O estudo investigou os efeitos agudos e crônicos da suplementação de bebida energética (BE) nos parâmetros cardiovasculares de ratos espontaneamente hipertensos (SHR) submetidos a um teste de esforço máximo. Os ratos foram distribuídos em quatro grupos: ratos wistar água mineral (C0), SHR água mineral (SHRs), SHR com suplementação de BE 3,6 ml/Kg de massa do animal (SHR1) e SHR com suplementação de BE 7,2 ml/Kg de massa do animal (SHR2). Os animais dos grupos tratados foram submetidos à suplementação com BE (Red Bull Energy Drink® adquirida comercialmente) por gavagem e os do grupo água mineral receberam 7,2 ml de água mineral/Kg de massa corporal do animal, todos os dias, durante um período de 30 dias. A pressão arterial (PA) e massa corporal foram medidas uma vez por semana e no começo e no final do experimento os animais foram submetidos à realização de teste para avaliar a tolerância ao esforço físico progressivo. O grupo SHR2 apresentou diferença significativa (p<0,05) nos valores de pressão arterial sistólica (PAS) no repouso quando comparado com os outros grupos depois de um período de ingestão energética. O uso do Red Bull Energy Drink® não alterou os valores pressóricos e a frequência cardíaca (FC) pré e pós teste máximo. Entretanto, no último teste máximo, os grupos que receberam BE apresentaram maior tolerância no teste de esforço máximo. Os resultados sugerem que os efeitos opostos da taurina e cafeína no sistema cardiovascular se equilibram quando ingeridas juntas, por isso a ingestão energética não influenciou de maneira decisiva no comportamento da PAS, da pressão arterial diastólica (PAD) e da FC pré e pós teste. Exceto no estado repouso quando ingerido a quantidade referente a dose de 7,2 ml/Kg de massa do animal, equivalente à ingestão de duas unidades de 250 ml por um ser humano de 70 kg de BE durante um período crônico, nesta situação a BE adquiriu caráter hipertensivo. A junção da hipertensão arterial (HA) com o uso do Red Bull Energy Drink® não interfere nos valores da PAS, da pressão arterial diastólica (PAD) e da FC pré e pós teste. O uso crônico somado a uma ingestão aguda antes da realização do teste aumenta a tolerância dos animais hipertensos, ao exercício físico progressivo. Cronicamente o uso do equivalente a duas latas de bebida energética durante o período de 30 dias é prejudicial para os animais hipertensos, aumentando ainda mais os valores da PAS.
The study investigated the acute and chronic effects of supplementation of energy drink (ED) on cardiovascular parameters in spontaneously hypertensive rats (SHR) submitted to a maximal exercise test. The rats were divided into four groups: mineral water Wistar rats (C0), mineral water SHR (SHR), SHR supplemented with ED 3.6 ml / kg of animal body weight of the animal (SHR1) and SHR supplemented with ED 7.2 ml / kg of animal body weight (SHR2). The animals in the treated groups were submitted to supplementation with ED (Red Bull Energy Drink ® commercially purchased) by gavage and the mineral water group received 7.2 ml mineral water/ kg of animal body weight, every day, for a period of 30 days. The blood pressure (BP) and body mass were measured once a week and at the beginning and end of the experiment the animals were submitted to the test to evaluate the tolerance to progressive physical effort. The group SHR2 presented significant difference (p <0.05) in systolic blood pressure (SBP) at rest when compared with the other groups after a period of energy intake. The use of Red Bull Energy Drink ® did not alter pressure values and heart rate (HR) pre and pos maximal test. However, in the last maximal test, the groups that received BE presented higher tolerance in the maximum exercise test. The results suggest that the opposite effects of taurine and caffeine on the cardiovascular system are balanced when ingested together, so energy intake did not influence decisively in the behavior of SBP, diastolic blood pressure (DBP) and HR pre and post test. Except in the rest state when the amount ingested referring to dose of 7.2 ml / kg of animal body weight ingesting equivalent to two units of 250 ml for a human being weighing 70 kg of ED over a chronic period, in this situation the ED has acquired character hypertensive. The combination of arterial hypertension (HA) using the Red Bull Energy Drink ® doesn’t interfere in SBP values, diastolic blood pressure (DBP) and HR pre and post test. The chronic use combined with a sharp intake before carrying out the test increases the tolerance of hypertensive animals to progressive physical exercise. Chronically the use of equivalent of two energy drink cans during the 30 day period is detrimental to hypertensive animals, further increasing values of SBP.
The study investigated the acute and chronic effects of supplementation of energy drink (ED) on cardiovascular parameters in spontaneously hypertensive rats (SHR) submitted to a maximal exercise test. The rats were divided into four groups: mineral water Wistar rats (C0), mineral water SHR (SHR), SHR supplemented with ED 3.6 ml / kg of animal body weight of the animal (SHR1) and SHR supplemented with ED 7.2 ml / kg of animal body weight (SHR2). The animals in the treated groups were submitted to supplementation with ED (Red Bull Energy Drink ® commercially purchased) by gavage and the mineral water group received 7.2 ml mineral water/ kg of animal body weight, every day, for a period of 30 days. The blood pressure (BP) and body mass were measured once a week and at the beginning and end of the experiment the animals were submitted to the test to evaluate the tolerance to progressive physical effort. The group SHR2 presented significant difference (p <0.05) in systolic blood pressure (SBP) at rest when compared with the other groups after a period of energy intake. The use of Red Bull Energy Drink ® did not alter pressure values and heart rate (HR) pre and pos maximal test. However, in the last maximal test, the groups that received BE presented higher tolerance in the maximum exercise test. The results suggest that the opposite effects of taurine and caffeine on the cardiovascular system are balanced when ingested together, so energy intake did not influence decisively in the behavior of SBP, diastolic blood pressure (DBP) and HR pre and post test. Except in the rest state when the amount ingested referring to dose of 7.2 ml / kg of animal body weight ingesting equivalent to two units of 250 ml for a human being weighing 70 kg of ED over a chronic period, in this situation the ED has acquired character hypertensive. The combination of arterial hypertension (HA) using the Red Bull Energy Drink ® doesn’t interfere in SBP values, diastolic blood pressure (DBP) and HR pre and post test. The chronic use combined with a sharp intake before carrying out the test increases the tolerance of hypertensive animals to progressive physical exercise. Chronically the use of equivalent of two energy drink cans during the 30 day period is detrimental to hypertensive animals, further increasing values of SBP.
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Citação
CARVALHO, Francine Pereira de. Efeito agudo e crônico da suplementação de bebida energética nos parâmetros cardiovasculares de ratos SHR submetidos ao teste de esforço máximo. 2012. 50 f. Trabalho de conclusão de curso de graduação (Educação Física) - Instituto Saúde e Sociedade,
Universidade Federal de São Paulo, Santos, 2013.