The prevalence of dementia in a Portuguese community sample: a 10/66 Dementia Research Group study

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dc.citation.volume17
dc.contributor.authorGoncalves-Pereira, Manuel
dc.contributor.authorCardoso, Ana
dc.contributor.authorVerdelho, Ana
dc.contributor.authorda Silva, Joaquim Alves
dc.contributor.authorde Almeida, Manuel Caldas
dc.contributor.authorFernandes, Alexandra
dc.contributor.authorRaminhos, Catia
dc.contributor.authorFerri, Cleusa P. [UNIFESP]
dc.contributor.authorMatthew Prina, A.
dc.contributor.authorPrince, Martin
dc.contributor.authorXavier, Miguel
dc.coverageLondon
dc.date.accessioned2020-09-01T13:21:17Z
dc.date.available2020-09-01T13:21:17Z
dc.date.issued2017
dc.description.abstractBackground: Dementia imposes a high burden of disease worldwide. Recent epidemiological studies in European community samples are scarce. In Portugal, community prevalence data is very limited. The 10/66 Dementia Research Group (DRG) population-based research programmes are focused in low and middle income countries, where the assessments proved to be culture and education fair. We applied the 10/66 DRG prevalence survey methodology in Portugal, where levels of illiteracy in older populations are still high. Methods: A cross-sectional comprehensive one-phase survey was conducted of all residents aged 65 and over of two geographically defined catchment areas in Southern Portugal (one urban and one rural site). Nursing home residents were not included in the present study. Standardized 10/66 DRG assessments include a cognitive module, an informant interview and the Geriatric Mental State-AGECAT, providing data on dementia diagnosis and subtypes, mental disorders including depression, physical health, anthropometry, demographics, disability/functioning, health service utilization, care arrangements and caregiver strain. Results: We interviewed 1405 old age participants (mean age 74.9, SD = 6.7 years; 55.5% women) after 313 (18.2%) refusals to participate. The prevalence rate for dementia in community-dwellers was 9.23% (95% CI 7.80-10.90) using the 10/66 DRG algorithm and 3.65% (95% CI 2.97-4.97) using DSM-IV criteria. Pure Alzheimer's disease was the most prevalent dementia subtype (41.9%). The prevalence of dementia was strongly age-dependent for both criteria, but there was no association with sex. Conclusions: Dementia prevalence was higher than previously reported in Portugal. The discrepancy between prevalence according to the 10/66 DRG algorithm and the DSM-IV criteria is consistent with that observed in less developed countries; this suggests potential underestimation using the latter approach, although relative validity of these two approaches remains to be confirmed in the European context. We improved the evidence base to raise awareness and empower advocacy about dementia in Portugal, so that the complex needs of frail older people may be met in better ways.en
dc.description.affiliationUniv Nova Lisboa, Fac Ciencias Med, Nova Med Sch, Chron Dis Res Ctr CEDOC, Campo Martires Patria 130, P-1169056 Lisbon, Portugal
dc.description.affiliationUniv Lisbon, Fac Med, Dept Neurosci, H Santa Maria CHLN, Lisbon, Portugal
dc.description.affiliationUniv Lisbon, Fac Med, IMM, Lisbon, Portugal
dc.description.affiliationUniv Lisbon, Fac Med, ISAMB, Lisbon, Portugal
dc.description.affiliationChampalimaud Ctr Unknown, Champalimaud Neurosci Programme, Lisbon, Portugal
dc.description.affiliationUniao Misericordias Portuguesas, Santa Casa Misericordia Mora, Mora, Portugal
dc.description.affiliationACES Almada Seixal, USF Fernao Ferro Mais, Seixal, Portugal
dc.description.affiliationKings Coll London, Ctr Global Mental Hlth Hlth Serv & Populat Res, Inst Psychiat Psychol & Neurosci, De Crespigny Pk, London SE5 8AF, England
dc.description.affiliationUniv Fed Sao Paulo, Dept Psychobiol, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Psychobiol, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFCT - Fundacao para a Ciencia e a Tecnologia
dc.description.sponsorshipPortuguese national funding agency for science, research and technology [PTDC/SAU-EPI/113652/2009]
dc.description.sponsorshipMRC [MR/K021907/1]
dc.description.sponsorshipFundacao para a Ciencia e Tecnologia / Ministerio da Educacao e Ciencia [iNOVA4Health - UID/Multi/04462/2013]
dc.description.sponsorshipFEDER
dc.description.sponsorshipIDPortuguese national funding agency for science, research and technology: PTDC/SAU-EPI/113652/2009
dc.description.sponsorshipIDMRC: MR/K021907/1
dc.description.sponsorshipIDFundacao para a Ciencia e Tecnologia / Ministerio da Educacao e Ciencia: iNOVA4Health - UID/Multi/04462/2013
dc.format.extent-
dc.identifierhttp://dx.doi.org/10.1186/s12877-017-0647-5
dc.identifier.citationBmc Geriatrics. London, v. 17, p. -, 2017.
dc.identifier.doi10.1186/s12877-017-0647-5
dc.identifier.fileWOS000414806400002.pdf
dc.identifier.issn1471-2318
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/58179
dc.identifier.wosWOS:000414806400002
dc.language.isoeng
dc.publisherBiomed Central Ltd
dc.relation.ispartofBmc Geriatrics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDementiaen
dc.subjectAlzheimer's diseaseen
dc.subjectEpidemiologyen
dc.subjectPrevalenceen
dc.subjectQuestionnairesen
dc.subjectCross-cultural psychiatryen
dc.titleThe prevalence of dementia in a Portuguese community sample: a 10/66 Dementia Research Group studyen
dc.typeinfo:eu-repo/semantics/article
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