Cancer treatment in determination of hearing loss

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dc.contributor.authorde Oliveira, Priscila Feliciano
dc.contributor.authorOliveira, Camila Silva
dc.contributor.authorAndrade, Joice Santos
dc.contributor.authordo Carmo Santos, Tamara Figueiredo
dc.contributor.authorde Oliveira-Barreto, Aline Cabral [UNIFESP]
dc.date.accessioned2019-01-21T10:30:06Z
dc.date.available2019-01-21T10:30:06Z
dc.date.issued2016
dc.description.abstractIntroduction: Chemotherapy and radiotherapy in oncology have repercussions in hearing health, and can damage structures of the inner ear. These repercussions usually, result in a bilateral and irreversible hearing loss. Objective: To identify sensorineural hearing toss cases with complaints of tinnitus and difficulty in speech understanding and investigate their relationship with the types of chemotherapy and radiotherapy the patients received. Methods: Cross-sectional, clinical, observational, analytical, historical cohort study of 58 subjects treated in a public hospital in the state of Sergipe, diagnosed with neoplasia. The subjects were submitted to anamnesis, conventional pure tone audiometry, and speech recognition threshold. Results: Of the 116 ears, 25.9% presented sensorioneural hearing loss characterized by changes in high frequencies. There was a positive correlation between hearing loss and the association of chemotherapy and radiotherapy (p= 0.035en
dc.description.abstractR=0.196). The auditory complaint analysis shows that most of the subjects had tinnitus and speech understanding difficulty, even with a normal auditory threshold. Conclusions: Cancer treatment causes hearing loss, associated with the administration of chemotherapy and radiotherapy. Cyclophosphamide increased the risk of causing hearing loss. Complaints of tinnitus and speech understanding difficulty were observed. (C) 2015 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda. All rights reserved.en
dc.description.affiliationUniversidade Federal de Sergipe (UFS), São Cristóvão, SE, Brasil, Programa Ciências da Saúde
dc.description.affiliationUniversidade Federal de Sergipe (UFS), São Cristovão, SE, Brasil, Departamento de Fonoaudiologia
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brasil, Programa de Fonoaudiologia
dc.description.affiliationUnifespUniversidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brasil, Programa de Fonoaudiologia
dc.description.sourceWeb of Science
dc.format.extent65-69
dc.identifierhttp://dx.doi.org/10.1016/j.bjorl.2014.12.010
dc.identifier.citationBrazilian Journal Of Otorhinolaryngology. Sao paulo, v. 82, n. 1, p. 65-69, 2016.
dc.identifier.doi10.1016/j.bjorl.2014.12.010
dc.identifier.fileS1808-86942016000100065.pdf
dc.identifier.issn1808-8694
dc.identifier.scieloS1808-86942016000100065
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/49586
dc.identifier.wosWOS:000371652200010
dc.language.isoeng
dc.publisherAssoc brasileira otorrinolaringologia & cirurgia cervicofacial
dc.relation.ispartofBrazilian Journal Of Otorhinolaryngology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCanceren
dc.subjectHearing Lossen
dc.subjectChemotherapyen
dc.subjectRadiotherapyRadiotherapyen
dc.subjectCisplatinen
dc.subjectHeaden
dc.titleCancer treatment in determination of hearing lossen
dc.titleTratamento oncológico na determinação das alterações auditivaspt
dc.typeinfo:eu-repo/semantics/article
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