Long-term effects of early malnutrition on body weight regulation

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dc.contributor.authorSawaya, Ana Lydia [UNIFESP]
dc.contributor.authorMartins, Paula Andrea [UNIFESP]
dc.contributor.authorGrillo, Luciane Peter
dc.contributor.authorFlorêncio, Telma Maria de Menezes Toledo
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Vale Itajai
dc.contributor.institutionUniv Fed Alagoas
dc.date.accessioned2016-01-24T12:37:14Z
dc.date.available2016-01-24T12:37:14Z
dc.date.issued2004-07-01
dc.description.abstractMalnutrition is still highly prevalent in developing countries. Studies have shown an increase in the number of obese individuals in very poor urban communities. This review shows a co-existence between malnutrition and obesity in households of slums in Brazil and a higher prevalence of stunted/overweight or obese individuals (30%) in comparison with stunted/underweight (16%). These conditions are associated with important metabolic changes. Results from stunted children showed higher susceptibility to the effects of higher fats diets, lower fat oxidation, higher central fat, and higher body fat gain. A model to explain how early malnutrition alters energy balance in adults is outlined. in the presence of a relative food intake insufficiency, a higher corti-sol:insulin ratio, associated with lower levels of IGF-1 will lead to lower muscle gain and linear growth, impaired lypolysis and fat oxidation. When these hormonal changes are combined with a higher fat/carbohydrate and/or marked decreased in physical activity, obesity with short stature will occur. Key words: malnutrition, stunting, obesity, body weight regulation (c) 2004 International Life Sciences Institute.en
dc.description.affiliationUniversidade Federal de São Paulo, Disciplina Neurofisiol & Fisiol Endocrina, Dept Fisiol, BR-04023060 São Paulo, Capital, Brazil
dc.description.affiliationUniv Vale Itajai, BR-88330000 Balneario Comboriu, SC, Brazil
dc.description.affiliationUniv Fed Alagoas, Dept Nutr, BR-87035220 Maceio, Alagoas, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Disciplina Neurofisiol & Fisiol Endocrina, Dept Fisiol, BR-04023060 São Paulo, Capital, Brazil
dc.description.sourceWeb of Science
dc.format.extentS127-S133
dc.identifierhttps://onlinelibrary.wiley.com/doi/10.1111/j.1753-4887.2004.tb00082.x/abstract
dc.identifier.citationNutrition Reviews. Washington: Int Life Sciences Inst North America, v. 62, n. 7, p. S127-S133, 2004.
dc.identifier.doi10.1301/nr.2004.jul.S127-S133
dc.identifier.issn0029-6643
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/27812
dc.identifier.wosWOS:000227612100010
dc.language.isoeng
dc.publisherInt Life Sciences Inst North America
dc.relation.ispartofNutrition Reviews
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMalnutritionen
dc.subjectStuntingen
dc.subjectObesityen
dc.subjectBody weight regulationen
dc.titleLong-term effects of early malnutrition on body weight regulationen
dc.typeinfo:eu-repo/semantics/article
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