Could acupuncture at the so-called forbidden points be harmful to the health of pregnant Wistar rats?

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dc.contributor.authorGuerreiro da Silva, Andre Vilella [UNIFESP]
dc.contributor.authorNakamura, Mary Uchiyama [UNIFESP]
dc.contributor.authorSilva, João Bosco Guerreiro da
dc.contributor.authorCordeiro, Jose Antonio
dc.contributor.authorMendes, Gloria Elisa Florido
dc.contributor.authorLima, Luiz
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionRio Preto Med Sch
dc.date.accessioned2016-01-24T14:31:52Z
dc.date.available2016-01-24T14:31:52Z
dc.date.issued2013-06-01
dc.description.abstractAim This study is the second report from a single experiment planned to determine if acupuncture at LI4 and SP6, or at the sacral points, could produce any harm in the pregnancy outcome of Wistar rats, as has been hypothesised in traditional knowledge. Here, we observe if these points can be harmful to the health of pregnant Wistar rats.Methods A total of 48 pregnant Wistar rats were randomly divided into 4 groups: total control, where rats were left in cages without manipulation; anesthetised control, where rats were manipulated and anesthetised but did not receive electroacupuncture; and peripheral point and sacral point groups, where rats were anesthetised and received 6 sessions of electroacupuncture at 4 acupuncture points: LI4 and SP6, and BL27 and BL28, respectively. in the 19th day of pregnancy the rats were killed and examined. the primary endpoints were levels of glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT) creatinine and histological changes of liver and kidney.Results There were no differences between the levels of biochemical parameters. No differences were also seen regarding the histopathological analysis.Conclusions We found no evidence that acupuncture at the LI4, SP6 and sacral points could be harmful to the Wistar rat dams.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.affiliationRio Preto Med Sch, Dept Med 2, Serv Acupuncture, BR-15015770 Sao Jose Do Rio Preto, SP, Brazil
dc.description.affiliationRio Preto Med Sch, Dept Stat, BR-15015770 Sao Jose Do Rio Preto, SP, Brazil
dc.description.affiliationRio Preto Med Sch, Dept Med 1, BR-15015770 Sao Jose Do Rio Preto, SP, Brazil
dc.description.affiliationRio Preto Med Sch, Dept Pathol, BR-15015770 Sao Jose Do Rio Preto, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent202-206
dc.identifierhttps://dx.doi.org/10.1136/acupmed-2012-010246
dc.identifier.citationAcupuncture in Medicine. London: Bmj Publishing Group, v. 31, n. 2, p. 202-206, 2013.
dc.identifier.doi10.1136/acupmed-2012-010246
dc.identifier.issn0964-5284
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/36417
dc.identifier.wosWOS:000319967900011
dc.language.isoeng
dc.publisherBmj Publishing Group
dc.relation.ispartofAcupuncture in Medicine
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.titleCould acupuncture at the so-called forbidden points be harmful to the health of pregnant Wistar rats?en
dc.typeinfo:eu-repo/semantics/article
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