Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
Data
2005-01-01
Autores
Soares, Angela Maria Victoriano de Campos 
Meira, Domingos Alves
Tipo
Artigo
Título da Revista
ISSN da Revista
Título de Volume
Resumo
In this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 mu g of glucan by i.p. route, were assayed. In vivo mu-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.
Descrição
Citação
Physiological Research. Prague 4: Acad Sciences Czech Republic, Inst Physiology, v. 54, n. 5, p. 557-564, 2005.