Fetal hydrocephalus

dc.contributor.authorCavalheiro, Sergio [UNIFESP]
dc.contributor.authorMoron, Antonio Fernandes [UNIFESP]
dc.contributor.authorAlmodin, Carlos Gilberto [UNIFESP]
dc.contributor.authorSuriano, Italo Capraro [UNIFESP]
dc.contributor.authorHisaba, Vagner [UNIFESP]
dc.contributor.authorDastoli, Patricia [UNIFESP]
dc.contributor.authorBarbosa, Mauricio Mendes [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:17:16Z
dc.date.available2016-01-24T14:17:16Z
dc.date.issued2011-10-01
dc.description.abstractIntroduction Hydrocephalus is the most frequent and devastating illness affecting a fetus. the development of both ultrasonography and magnetic resonance, associated with laboratorial tests, has greatly facilitated its diagnosis.Materials and methods in the Fetal Medicine Service of the Federal University of São Paulo and in the Santa Joana/Pro-Matre Paulista Hospital Complex, in São Paulo, SP, Brazil, repeated cephalocenteses, ventricular-amniotic shunting, and neuroendoscopy were used to treat 57 fetuses with hydrocephalus, all of them at a gestational age under 32 weeks. Another eight fetuses had myelomeningocele and underwent correctional open surgery to prevent hydrocephalus.Results Thirty-nine patients were followed up for a period longer than 3 years and had their intelligence coefficient assessed: 26 of them were considered normal (IQ above 70); six had mild or moderate handicaps (IQ from 35 to 70), and seven were severely handicapped (IQ below 35). Out of the eight patients operated for correction of myelomeningocele, only two came to require shunting. There were no cases of maternal morbidity, and no infectious condition was observed in any of the patients subjected to intrauterine treatment.Conclusion Selected cases of isolated, evolutive, non-destructive hydrocephaly diagnosed before 32 gestational weeks may benefit from fetal neurosurgical procedures. With the accuracy improvement of diagnoses, the number of patients fitting into that group has become very small.en
dc.description.affiliationUniversidade Federal de São Paulo, Sect Pediat Neurosurg, BR-04023062 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Obstet, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Sect Pediat Neurosurg, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Obstet, BR-04023062 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1575-1583
dc.identifierhttp://dx.doi.org/10.1007/s00381-011-1539-1
dc.identifier.citationChilds Nervous System. New York: Springer, v. 27, n. 10, p. 1575-1583, 2011.
dc.identifier.doi10.1007/s00381-011-1539-1
dc.identifier.issn0256-7040
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34092
dc.identifier.wosWOS:000295848500009
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofChilds Nervous System
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.subjectFetal hydrocephalusen
dc.subjectCephalocentesisen
dc.subjectVentriculo-amniotic shuntingen
dc.subjectNeuroendoscopyen
dc.subjectMyelomeningoceleen
dc.subjectViral infectionen
dc.titleFetal hydrocephalusen
dc.typeinfo:eu-repo/semantics/article
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