Opposite effects of neonatal hypoxia on acute amphetamine-induced hyperlocomotion in adult and adolescent mice

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dc.contributor.authorKameda, Sonia R. [UNIFESP]
dc.contributor.authorFukushiro, Daniela F. [UNIFESP]
dc.contributor.authorWuo-Silva, Raphael [UNIFESP]
dc.contributor.authorTrombin, Thais F. [UNIFESP]
dc.contributor.authorProcopio-Souza, Roberta [UNIFESP]
dc.contributor.authorBrandao, Leticia C. [UNIFESP]
dc.contributor.authorSanday, Leandro [UNIFESP]
dc.contributor.authorPatti, Camilla L. [UNIFESP]
dc.contributor.authorMari-Kawamoto, Elisa [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.authorD'Almeida, Vania [UNIFESP]
dc.contributor.authorFrussa-Filho, Roberto [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:31:53Z
dc.date.available2016-01-24T14:31:53Z
dc.date.issued2013-06-30
dc.description.abstractWe investigated whether the effect of neonatal hypoxia on amphetamine-induced hyperlocomotion can reproduce the ontogenic (age of onset) properties of schizophrenia. Neonatal hypoxia enhanced amphetamine-induced hyperlocomotion in adult mice and decreased it in adolescent mice. These findings provide ontogenic validity for this very simple animal model of schizophrenia. (C) 2013 Elsevier Ireland Ltd. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Pharmacol, BR-04023062 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Psychobiol, BR-04024002 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Pediat, BR-04023062 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Biosci, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Pharmacol, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Psychobiol, BR-04024002 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Pediat, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Biosci, BR-11060001 Santos, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundo de Apoio ao Docente e Aluno (FADA)
dc.description.sponsorshipAssociacao Fundo de Incentivo a Pesquisa (AFIP)
dc.format.extent74-77
dc.identifierhttp://dx.doi.org/10.1016/j.psychres.2013.03.021
dc.identifier.citationPsychiatry Research. Clare: Elsevier B.V., v. 208, n. 1, p. 74-77, 2013.
dc.identifier.doi10.1016/j.psychres.2013.03.021
dc.identifier.issn0165-1781
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/36436
dc.identifier.wosWOS:000320819700012
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofPsychiatry Research
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectAgeen
dc.subjectAmphetamineen
dc.subjectNeonatal hypoxiaen
dc.titleOpposite effects of neonatal hypoxia on acute amphetamine-induced hyperlocomotion in adult and adolescent miceen
dc.typeinfo:eu-repo/semantics/article
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