Neuropsychological Assessment of Current and Past Crack Cocaine Users
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2009-01-01
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Sanchez, Zila Van Der Meer 
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Background: Cognitive changes due to crack cocaine consumption remain unclear Methods: for clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory Mood state was also measured. Intergroup comparisons were carried out. Results: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). Conclusion: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence.
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Substance Use & Misuse. London: Informa Healthcare, v. 44, n. 13, p. 1941-1957, 2009.