Cardiovascular control in experimental diabetes

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dc.contributor.authorDe Angelis, Katia
dc.contributor.authorSchaan, Beatriz D'Agord
dc.contributor.authorMaeda, C.y.
dc.contributor.authorDal Lago, Pedro
dc.contributor.authorWichi, Rogerio Brandao [UNIFESP]
dc.contributor.authorIrigoyen, Maria Claudia [UNIFESP]
dc.contributor.institutionUniversidade de Santo Amaro UNIPESQ Laboratório de Cardiovascular
dc.contributor.institutionUniversidade Federal do Rio Grande do Sul Instituto de Ciências Básicas da Saúde Departamento de Fisiologia
dc.contributor.institutionInstituto de Cardiologia do Rio Grande do Sul Fundação Universitária de Cardiologia
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionPontifícia Universidade Católica do Rio Grande do Sul FAENFI Curso de Fisioterapia
dc.date.accessioned2015-06-14T13:29:47Z
dc.date.available2015-06-14T13:29:47Z
dc.date.issued2002-09-01
dc.description.abstractSeveral studies have reported impairment in cardiovascular function and control in diabetes. The studies cited in this review were carried out from a few days up to 3 months after streptozotocin administration and were concerned with the control of the circulation. We observed that early changes (5 days) in blood pressure control by different peripheral receptors were maintained for several months. Moreover, the impairment of reflex responses observed after baroreceptor and chemoreceptor stimulation was probably related to changes in the efferent limb of the reflex arc (sympathetic and parasympathetic), but changes also in the central nervous system could not be excluded. Changes in renal sympathetic nerve activity during volume expansion were blunted in streptozotocin-treated rats, indicating an adaptive natriuretic and diuretic response in the diabetic state. The improvement of diabetic cardiovascular dysfunction induced by exercise training seems to be related to changes in the autonomic nervous system. Complementary studies about the complex interaction between circulation control systems are clearly needed to adequately address the management of pathophysiological changes associated with diabetes.en
dc.description.affiliationUniversidade de Santo Amaro UNIPESQ Laboratório de Cardiovascular
dc.description.affiliationUniversidade Federal do Rio Grande do Sul Instituto de Ciências Básicas da Saúde Departamento de Fisiologia
dc.description.affiliationInstituto de Cardiologia do Rio Grande do Sul Fundação Universitária de Cardiologia
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Nefrologia
dc.description.affiliationUniversidade de São Paulo Faculdade de Medicina Hospital das Clínicas
dc.description.affiliationPontifícia Universidade Católica do Rio Grande do Sul FAENFI Curso de Fisioterapia
dc.description.affiliationUnifespUNIFESP, EPM, Depto. de Nefrologia
dc.description.sourceSciELO
dc.format.extent1091-1100
dc.identifierhttp://dx.doi.org/10.1590/S0100-879X2002000900010
dc.identifier.citationBrazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 35, n. 9, p. 1091-1100, 2002.
dc.identifier.doi10.1590/S0100-879X2002000900010
dc.identifier.fileS0100-879X2002000900010.pdf
dc.identifier.issn0100-879X
dc.identifier.scieloS0100-879X2002000900010
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/1514
dc.identifier.wosWOS:000179344000010
dc.language.isoeng
dc.publisherAssociação Brasileira de Divulgação Científica
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectExperimental diabetesen
dc.subjectArterial pressureen
dc.subjectAutonomic controlen
dc.subjectBaroreflexen
dc.subjectChemoreflexen
dc.subjectCardiopulmonary reflexen
dc.subjectExercise trainingen
dc.titleCardiovascular control in experimental diabetesen
dc.typeinfo:eu-repo/semantics/article
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