Psychological stress as a risk factor for postoperative keloid recurrence

Data
2012-04-01
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Objective: To investigate psychological stress on the prognosis of the postoperative recurrence of keloids.Methods: Patients with keloids (n=25), candidates for surgical resection and postoperative radiotherapy, had their psychological stress evaluated on the day before the surgical procedure. the parameters evaluated were pain and itching (Visual Numerical Scale), quality of life (Questionnaire QualiFibro/Cirurgia Plastica-UNIFESP), perceived stress (Perceived Stress Scale), depression and anxiety (Hospital Depression and Anxiety Scale), salivary cortisol and minimum and maximum galvanic skin responses (GSR) at rest and under stress (i.e., while the questionnaires were being filled out). Patients were evaluated during the 3rd, 6th, 9th and 12th months of postoperative care. During each return visit, two experts classified the lesions as non-recurrent and recurrent.Results: the recurrence group presented the greatest values in GSR during a stressful situation. the chance of recurrence increased by 34% at each increase of 1000 arbitrary units in maximum GSR during stress.Conclusion: Psychological stress influenced the recurrence of keloids. (C) 2012 Elsevier Inc. All rights reserved.
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Journal of Psychosomatic Research. Oxford: Pergamon-Elsevier B.V., v. 72, n. 4, p. 282-287, 2012.
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