Study of rabbit septal cartilage grafts placed on the nasal dorsum

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dc.contributor.authorSouza, Marcia Maria Ale de [UNIFESP]
dc.contributor.authorGregório, Luiz Carlos [UNIFESP]
dc.contributor.authorSesso, Ricardo de Castro Cintra [UNIFESP]
dc.contributor.authorSouza, Soraia Ale [UNIFESP]
dc.contributor.authorSettanni, Flavio Aurélio Parente [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-15T13:56:00Z
dc.date.available2018-06-15T13:56:00Z
dc.date.issued2008-07-01
dc.description.abstractObjective: To compare the reabsorption characteristics of fresh septal cartilage autografts, preserved homografts, and preserved autografts in the nasal dorsum of rabbits.Methods: Rabbit nasal dorsum cartilage grafts were placed in 3 groups. The first group used fresh autologous cartilage; the second group, alcohol-preserved homologous cartilage; and the third group, alcohol-preserved autologous cartilage. Each rabbit received 2 grafts, one crushed and another noncrushed. After 16 weeks, the grafts were removed for analysis.Results: No graft calcification occurred in any group. Chondrogenesis was observed in all groups. The fresh autograft group had the best results in the evaluation of the area of graft recovered and chondrocyte viability. The preserved autologous and homologous grafts did not differ in relation to any of the variables analyzed. Crushed grafts had inferior results in the area of graft recovered and chondrocyte viability compared with the noncrushed forms. No significant difference among the 3 groups was noted in the thickness of the fibrous capsule that developed around the graft.Conclusions: The fresh cartilage autograft was superior to the crushed and uncrushed preserved homografts and autografts; both types of preserved grafts had equivalent histological results. The uncrushed forms were superior to the crushed forms.en
dc.description.affiliationUniv Fed Sao Paulo, Dept Med, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Div Rhinol, Dept Otolaryngol Head & Neck Surg, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Med, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Div Rhinol, Dept Otolaryngol Head & Neck Surg, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent250-254
dc.identifierhttp://dx.doi.org/10.1001/archfaci.10.4.250
dc.identifier.citationArchives Of Facial Plastic Surgery. Chicago: Amer Medical Assoc, v. 10, n. 4, p. 250-254, 2008.
dc.identifier.doi10.1001/archfaci.10.4.250
dc.identifier.issn1521-2491
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/42646
dc.identifier.wosWOS:000257754600006
dc.language.isoeng
dc.publisherAmer Medical Assoc
dc.relation.ispartofArchives Of Facial Plastic Surgery
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleStudy of rabbit septal cartilage grafts placed on the nasal dorsumen
dc.typeinfo:eu-repo/semantics/article
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