Histomorphometry of sexually immature albino rat testis after X ray-irradiation

dc.contributor.authorCabral, Maria das Gracas Botelho [UNIFESP]
dc.contributor.authorHayashi, Hisakazu [UNIFESP]
dc.contributor.authorMiraglia, Sandra Maria [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-15T17:44:09Z
dc.date.available2018-06-15T17:44:09Z
dc.date.issued1997-03-01
dc.description.abstractA A morphometric study was conducted of sexually immature albino rat testes which were exposed to a localized single. X-ray dose of 154.00 mC/Kg.The rats were killed at the ages of 25, 30, 35, 45, 60, 90 and 120 days. Their testes were removed from the scrota and examined microscopically by light microscope and macroscopically, To obtain better identification of all phases of spermatogenesis, 6 mu m-thick paraffin sections were stained using the periodic acid-Schiff (PAS) and Harris hematoxylin methods.The results show that X-rays provoke severe alterations in the seminiferous epithelium, selectively eliminating a significant quantity of the spermatogonia. On other hand, the elements which survived X-irradiation, including some types of spermatogonia and undifferentiated cells, were capable of repopulating the seminiferous epithelium. Animals irradiated at 25 days of age were found to be fertile when they were mated between 90 and 120 days.en
dc.description.affiliationUNIV FED SAO PAULO,ESCOLA PAULISTA MED,LAB EMBRYOL,DEPT MORPHOL,BR-04023900 SAO PAULO,BRAZIL
dc.description.affiliationUnifespUNIV FED SAO PAULO,ESCOLA PAULISTA MED,LAB EMBRYOL,DEPT MORPHOL,BR-04023900 SAO PAULO,BRAZIL
dc.description.sourceWeb of Science
dc.format.extent71-80
dc.identifier.citationInterciencia. Caracas: Interciencia, v. 22, n. 2, p. 71-80, 1997.
dc.identifier.issn0378-1844
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/43982
dc.identifier.wosWOS:A1997WP70800007
dc.language.isoeng
dc.publisherInterciencia
dc.relation.ispartofInterciencia
dc.rightsAcesso restrito
dc.subjecttestisen
dc.subjectspermatogenesisen
dc.subjectX-raysen
dc.subjectmorphometryen
dc.titleHistomorphometry of sexually immature albino rat testis after X ray-irradiationen
dc.typeArtigo
Arquivos
Coleções