Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats
Data
2015-02-01
Autores
Martins, Francielle
Renno, Ana Claudia Muniz [UNIFESP]
De Oliveira, Flavia [UNIFESP]
Minatel, Natália Peruchi
Bortolin, Jeferson André
Quintana, Hananiah Tardivo
Aveiro, Mariana Chaves [UNIFESP]
Orientadores
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Artigo
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Resumo
PURPOSE: To investigate the effectiveness of low-level laser therapy (LLLT) on gastrocnemius muscle morphology and Myod imunoexpression in a model of dorsal burn in rats. METHODS: Sixteen male Wistar rats were distributed into two groups: control group (CG): rats submitted to scald burn injury without treatment and laser treated group (LG): rats submitted to scald burn injury and treated with laser therapy. Fourteen days post-surgery, gastrocnemius muscle was evaluated being the specimens stained with HE and morphometric data was evaluated. MyoD expression was assessed by immunohistochemistry. RESULTS: The results showed that laser treated animals presented more organized tissue morphology compared to the non-treated animals, with a higher number of nucleus in the fibers. Also, the cross sectional area of the fibers and the MyoD immunoexpression in the laser treated groups was higher. CONCLUSION: Low-level laser therapy had positive effects on gastrocnemius muscle, improving tissue muscle morphology, increasing cross sectional area and MyoD immunoexpression.
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Citação
Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 30, n. 2, p. 94-99, 2015.