Clinical management of six cases of low-risk primary tonsillar non-Hodgkin´s lymphoma

Clinical management of six cases of low-risk primary tonsillar non-Hodgkin´s lymphoma

Author Colleoni, Gisele Wally Braga Autor UNIFESP Google Scholar
Oliveira, José Salvador Rodrigues de Autor UNIFESP Google Scholar
Alves, Antonio Correa Autor UNIFESP Google Scholar
Borducchi, Davimar Miranda Maciel Autor UNIFESP Google Scholar
Segreto, Roberto Araujo Autor UNIFESP Google Scholar
Cervantes, Onivaldo Autor UNIFESP Google Scholar
Kerbauy, José Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract CONTEXT: There have been many reports that favor aggressive systemic treatment with chemotherapy and radiotherapy, even for well-localized lymphomas, avoiding the need for tonsillectomy of the normal tonsil. CASE REPORT: We report six cases of primary tonsillar lymphoma with a median patient age of 42 years. There were two lymphoma cases with diffuse large cells, two cases with mixed small and large cells, one with small cells and one indeterminate. They were treated with six cycles of chemotherapy and cervical radiotherapy. All patients achieved durable complete remission. Our data agree with previous reports that suggested that primary tonsillar high-grade B-cell NHL has a good prognosis if aggressively treated.

CONTEXTO: Muitos trabalhos têm proposto tratamento sistêmico agressivo com quimioterapia e radioterapia para os linfomas de tonsila palatina, mesmo tratando-se de tumores bem localizados, sem a necessidade de amidalectomia contralateral. RELATO DE CASO: Nós relatamos seis casos de linfoma primário de tonsila palatina, com idade mediana de 42 anos. Havia dois casos de linfoma difuso de grandes células, dois casos de linfoma de pequenas e grandes células, um caso de linfoma linfocítico de pequenas células e um caso indeterminado. Foram tratados com seis ciclos de quimioterapia e radioterapia cervical. Todos os pacientes atingiram remisão completa mantida. Nossos dados estão de acordo com relatos prévios que sugerem que os linfomas de células B têm bom prognóstico se agressivamente tratados.
Keywords Non-Hodgkin´s lymphoma
Linfoma não-Hodgkin
Tonsila palatina
Tratamento prognóstico
Language English
Date 1999-09-02
Published in São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 117, n. 5, p. 215-217, 1999.
ISSN 1516-3180 (Sherpa/Romeo)
Publisher Associação Paulista de Medicina - APM
Extent 215-217
Access rights Open access Open Access
Type Article
SciELO ID S1516-31801999000500006 (statistics in SciELO)

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