Now showing items 1-6 of 6
Identification of a Critical Window for Ganciclovir-Induced Disruption of Testicular Development in Rats
(Oxford Univ Press, 2018)
Ganciclovir (GCV) has been implicated in the development of testicular alterations. Exposure on gestational day (GD) 10 in rats induced permanent effects, including focal reduction or absence of germ cells (Sertoli cell-only ...
Histomorphometry of sexually immature albino rat testis after X ray-irradiation
A A morphometric study was conducted of sexually immature albino rat testes which were exposed to a localized single. X-ray dose of 154.00 mC/Kg.The rats were killed at the ages of 25, 30, 35, 45, 60, 90 and 120 days. Their ...
Late reproductive analysis in rat male offspring exposed to nicotine during pregnancy and lactation
We previously observed that nicotine, administered to rats (Wistar) during pregnancy and lactation periods, provokes, in the progeny, late morphofunctional alterations in Leydig cell, body weight increase in adulthood ...
In situ demonstration of both TUNEL-labeled germ cell and Sertoli cell in the cimetidine-treated rats
(F Hernandez, 2002-04-01)
Cimetidine has caused dysfunction in the male reproductive system. In the rat testis, intratubular alterations and loss of peritubular tissue due to peritubular myoid cell death by apoptosis have been recently shown. Thus, ...
Alterations of spermatogenesis in etoposide-treated rats: A stereological study
The etoposide is an anticancer drug that interacts with topoisomerase II. Thirty-day-old rats received intraperitonially 2mg/kg of etoposide for 30 consecutive days. Their testes were analyzed in the adult phase under light ...
Vitamin B-12-induced spermatogenesis recovery in cimetidine-treated rats: effect on the spermatogonia number and sperm concentration
(Medknow Publications & Media Pvt Ltd, 2017)
The H-2-receptor antagonist cimetidine is an antiulcer drug also used for the treatment of cancer due to its antiangiogenic effect. However, this drug has caused structural changes in the seminiferous tubules. Vitamin B-12 ...