Recent Submissions

  • The threat of emerging and re-emerging pathogenic Sporothrix species 

    Rodrigues, Anderson; Della Terra, Paula Portella; Gremião, Isabella Dib; Pereira, Sandro Antonio; Orofino-Costa, Rosane; de Camargo, Zoilo Pires (Ferry Hagen, 2020-02-12)
  • Sporothrix chilensis sp nov (Ascomycota: Ophiostomatales), a soil-borne agent of human sporotrichosis with mild-pathogenic potential to mammals 

    Rodrigues, Anderson Messias [UNIFESP]; Cruz Choappa, Rodrigo; Fernandes, Geisa Ferreira [UNIFESP]; De Hoog, G. Sybren; De Camargo, Zoilo Pires [UNIFESP] (Elsevier Sci Ltd, 2016)
    A combination of phylogeny, evolution, morphologies and ecologies has enabled major advances in understanding the taxonomy of Sporothrix species, including members exhibiting distinct lifestyles such as saprobes, human/animal ...
  • Human TNF-alpha induces differential protein phosphorylation in Schistosoma mansoni adult male worms 

    Oliveira, Katia C. [UNIFESP]; Carvalho, Mariana L. P.; Bonatto, Jose Matheus C.; Schechtman, Debora; Verjovski-Almeida, Sergio (Springer, 2016)
    Schistosoma mansoni and its vertebrate host have a complex and intimate connection in which several molecular stimuli are exchanged and affect both organisms. Human tumor necrosis factor alpha (hTNF-alpha), a pro-inflammatory ...
  • Sporothrix chilensis sp nov (Ascomycota: Ophiostomatales), a soil-borne agent of human sporotrichosis with mild-pathogenic potential to mammals 

    Rodrigues, Anderson Messias [UNIFESP]; Cruz Choappa, Rodrigo; Fernandes, Geisa Ferreira [UNIFESP]; De Hoog, G. Sybren; De Camargo, Zoilo Pires [UNIFESP] (Elsevier Sci Ltd, 2016)
    A combination of phylogeny, evolution, morphologies and ecologies has enabled major advances in understanding the taxonomy of Sporothrix species, including members exhibiting distinct lifestyles such as saprobes, human/animal ...
  • Human TNF-alpha induces differential protein phosphorylation in Schistosoma mansoni adult male worms 

    Oliveira, Katia C. [UNIFESP]; Carvalho, Mariana L. P.; Bonatto, Jose Matheus C.; Schechtman, Debora; Verjovski-Almeida, Sergio (Springer, 2016)
    Schistosoma mansoni and its vertebrate host have a complex and intimate connection in which several molecular stimuli are exchanged and affect both organisms. Human tumor necrosis factor alpha (hTNF-alpha), a pro-inflammatory ...
  • Clotrimazole is highly effective in vitro against feline Sporothrix brasiliensis isolates 

    Gagini, Thalita; Borba-Santos, Luana Pereira; Rodrigues, Anderson Messias [UNIFESP]; de Camargo, Zoilo Pires [UNIFESP]; Rozental, Sonia (Microbiology Soc, 2017)
    Purpose. Sporothrix brasiliensis, the most virulent species in the Sporothrix schenckii complex, is responsible for the ongoing epidemics of human and animal sporotrichosis in Brazil. Feline outbreaks are usually driven ...
  • Enteroaggregative Escherichia coli with uropathogenic characteristics are present in feces of diarrheic and healthy children 

    Nunes, Kamila O.; Santos, Adriana C. P.; Bando, Silvia Y.; Silva, Rosa M. [UNIFESP]; Gomes, Tania A. T. [UNIFESP]; Elias, Waldir P. (Oxford Univ Press, 2017)
    Enteroaggregative Escherichia coli (EAEC) has been recently associated with urinary tract infections (UTI). Since EAEC are found in feces of both diarrheic and asymptomatic individuals, their presence in the intestine may ...
  • Galectin-3: A Friend but Not a Foe during Trypanosoma cruzi Experimental Infection 

    da Silva, Aline A.; Teixeira, Thaise L.; Teixeira, Samuel C.; Machado, Fabricio C. [UNIFESP]; dos Santos, Marlus A.; Tomiosso, Tatiana C.; Tavares, Paula C. B.; e Silva Brigido, Rebecca T.; Martins, Flavia Alves; de Lira Silva, Nadjania S. [UNIFESP]; Rodrigues, Cassiano C.; Roque-Barreira, Maria C.; Mortara, Renato A. [UNIFESP]; Lopes, Daiana S.; Rodrigues Avila, Veridiana de Melo; da Silva, Claudio V. (Frontiers Media Sa, 2017)
    Trypanosoma cruzi interacts with host cells, including cardiomyocytes, and induces the production of cytokines, chemokines, metalloproteinases, and glycan-binding proteins. Among the glycan-binding proteins is Galectin-3 ...
  • ERM Proteins Play Distinct Roles in Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi 

    Ferreira, Eden R. [UNIFESP]; Bonfim-Melo, Alexis [UNIFESP]; Cordero, Esteban M.; Mortara, Renato A. [UNIFESP] (Frontiers Media Sa, 2017)
    The protozoan parasite Trypanosoma cruzi is the causative agent of Chagas' disease. In mammalian hosts, T. cruzi alternates between trypomastigote and amastigote forms. Additionally, trypomastigotes can differentiate into ...
  • Comparative transcriptome profiling of virulent and non-virulent Trypanosoma cruzi underlines the role of surface proteins during infection 

    Belew, A. Trey; Junqueira, Caroline; Rodrigues-Luiz, Gabriela F.; Valente, Bruna M.; Oliveira, Antonio Edson R.; Polidoro, Rafael B. [UNIFESP]; Zuccherato, Luciana W.; Bartholomeu, Danielle C.; Schenkman, Sergio [UNIFESP]; Gazzinelli, Ricardo T.; Burleigh, Barbara A.; Ei-Sayed, Najib M.; Teixeira, Santuza M. R. (Public Library Science, 2017)
    Trypanosoma cruzi, the protozoan that causes Chagas disease, has a complex life cycle involving several morphologically and biochemically distinct stages that establish intricate interactions with various insect and mammalian ...
  • Myeloperoxidase in human peripheral blood lymphocytes: Production and subcellular localization 

    Okada, Sabrina Sayori; de Oliveira, Edson Mendes; de Araujo, Tomaz Henrique; Rodrigues, Maria Rita; Albuquerque, Renata Chaves; Mortara, Renato Arruda [UNIFESP]; Taniwaki, Noemi Nosomi; Nakaya, Helder Imoto; Campa, Ana; Ramos Moreno, Ana Carolina (Academic Press Inc Elsevier Science, 2016)
    Myeloperoxidase (MPO) is an important enzyme in the front-line protection against microorganisms. In peripheral blood, it is accepted that MPO is only produced by myeloid-lineage cells. Thus, MPO presence is unexpected in ...
  • Antibodies Against Glycolipids Enhance Antifungal Activity of Macrophages and Reduce Fungal Burden After Infection with Paracoccidioides brasiliensis 

    Bueno, Renata A.; Thomaz, Luciana; Munoz, Julian E.; da Silva, Cassia J.; Nosanchuk, Joshua D.; Pinto, Marcia R.; Travassos, Luiz R. [UNIFESP]; Taborda, Carlos P. (Frontiers Media Sa, 2016)
    Paracoccidioidomycosis is a fungal disease endemic in Latin America. Polyclonal antibodies to acidic glycosphingolipids (GSLs) from Paracoccidioides brasiliensis opsonized yeast forms in vitro increasing phagocytosis and ...
  • The Mitogen-Activated Protein Kinase (MAPK) Pathway: Role in Immune Evasion by Trypanosomatids 

    Soares-Silva, Mercedes; Diniz, Flavia F.; Gomes, Gabriela N.; Bahia, Diana [UNIFESP] (Frontiers Media Sa, 2016)
    Leishrnania spp. and Trypanosome cruzi are the causative agents of leishmaniasis and Chagas disease, respectively, two neglected tropical diseases that affect about 25 million people worldwide. These parasites belong to ...
  • Protective effects of mito-TEMPO against doxorubicin cardiotoxicity in mice 

    Junqueira Rocha, Viviane Costa; de Aragao Franca, Luciana Souza; de Araujo, Cintia Figueiredo; Ng, Ayling Martins; de Andrade, Candace Machado; Andrade, Andre Cronemberger [UNIFESP]; Santos, Emanuelle de Souza; Borges-Silva, Mariana da Cruz; Macambira, Simone Garcia; Noronha-Dutra, Alberto Augusto; Pontes-de-Carvalho, Lain Carlos (Springer, 2016)
    Doxorubicin (DOX) is a chemotherapeutic that is widely used for the treatment of many human tumors. However, the development of cardiotoxicity has limited its use. The aim of the present study was to evaluate the possible ...
  • In vitro susceptibility of antifungal drugs against Sporothrix brasiliensis recovered from cats with sporotrichosis in Brazil 

    Nogueira Brilhante, Raimunda Samia [UNIFESP]; Rodrigues, Anderson Messias [UNIFESP]; Costa Sidrim, Jose Julio [UNIFESP]; Gadelha Rocha, Marcos Fabio [UNIFESP]; Pereira, Sandro Antonio; Ferreira Gremiao, Isabella Dib; Pacheco Schubach, Tania Maria; de Camargo, Zoilo Pires [UNIFESP] (Oxford Univ Press, 2016)
    Sporotrichosis is an important subcutaneous mycosis of humans and animals. Classically, the disease is acquired upon traumatic inoculation of Sporothrix propagules from contaminated soil and plant debris. In addition, the ...
  • High incidence of tuberculosis in patients treated for hepatitis C chronic infection 

    de Oliveira Uehara, Silvia Naomi [UNIFESP]; Emori, Christini Takemi [UNIFESP]; Perez, Renata Mello; Jacintho Mendes-Correa, Maria Cassia; Paiva Ferreira, Adalgisa de Souza; de Castro Amaral Feldner, Ana Cristina [UNIFESP]; Benedito Silva, Antonio Eduardo [UNIFESP]; Carvalho Filho, Roberto Jose [UNIFESP]; de Souza e Silva, Ivonete Sandra [UNIFESP]; Cardoso Gomes Ferraz, Maria Lucia [UNIFESP] (Elsevier Brazil, 2016)
    Brazil is one of the 22 countries that concentrates 80% of global tuberculosis cases concomitantly to a large number of hepatitis C carriers and some epidemiological risk scenarios are coincident for both diseases. We ...
  • Antiretroviral drugs saquinavir and ritonavir reduce inhibitory concentration values of itraconazole against Histoplasma capsulatum strains in vitro 

    Nogueira Brilhante, Raimunda Samia; Caetano, Erica Pacheco; Riello, Giovanna Barbosa; de Melo Guedes, Glaucia Morgana; Collares Maia Castelo-Branco, Debora de Souza; Bezerra Fechine, Maria Auxiliadora; de Oliveira, Jonathas Sales; de Camargo, Zoilo Pires [UNIFESP]; Lima de Mesquita, Jaco Ricarte; Monteiro, Andre Jalles; Cordeiro, Rossana de Aguiar; Gadelha Rocha, Marcos Fabio; Costa Sidrim, Jose Julio (Elsevier Brazil, 2016)
    Recent studies have shown that some drugs that are not routinely used to treat fungal infections have antifungal activity, such as protease inhibitor antiretroviral drugs. This study investigated the in vitro susceptibility ...
  • triangle(24)-Sterol Methyltransferase Plays an Important Role in the Growth and Development of Sporothrix schenckii and Sporothrix brasiliensis 

    Borba-Santos, Luana P.; Visbal, Gonzalo; Gagini, Thalita; Rodrigues, Anderson M. [UNIFESP]; de Camargo, Zoilo P. [UNIFESP]; Lopes-Bezerra, Leila M.; Ishida, Kelly; de Souza, Wanderley; Rozental, Sonia (Frontiers Media Sa, 2016)
    Inhibition of triangle(24)-sterol methyltransferase (24-SMT) in Sporothrix schenckii sensu stricto and Sporothrix brasiliensis was investigated in vitro. The effects on fungal growth and sterol composition of the 24-SMT ...
  • Interactions between Trypanosoma cruzi Secreted Proteins and Host Cell Signaling Pathways 

    Costa, Renata Watanabe [UNIEFSP]; da Silveira, Jose F. [UNIFESP]; Bahia, Diana [UNIFESP] (Frontiers Media Sa, 2016)
    Chagas disease is one of the prevalent neglected tropical diseases, affecting at least 6-7 million individuals in Latin America. It is caused by the protozoan parasite Trypanosoma cruzi, which is transmitted to vertebrate ...
  • Is Malassezia nana the main species in horses' ear canal microbiome? 

    Aldrovandi, Ana Lucia; Osugui, Lika [UNIFESP]; Acqua Coutinho, Selene Dall' (Soc Brasileira Microbiologia, 2016)
    The objective of this study was to characterize genotypically Malassezia spp. isolated from the external ear canal of healthy horses. Fifty-five horses, 39 (70.9%) males and 16 (29.1%) females, from different breeds and ...

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