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Is Selective Digestive Decontamination Useful for Critically Ill Patients?
(Lippincott Williams & Wilkins, 2017)
In this study we review the rationale for using selective digestive decontamination (SDD) in critically ill patients, and its effects on clinical outcomes and rates of infection with antimicrobial-resistant microorganisms. ...
The polymyxin B-induced transcriptomic response of a clinical, multidrug-resistant Klebsiella pneumoniae involves multiple regulatory elements and intracellular targets
(Biomed Central Ltd, 2016)
Background: The emergence of multidrug-resistant Klebsiella pneumoniae is a major public health concern. Many K. pneumoniae infections can only be treated when resorting to last-line drugs such as polymyxin B (PB). However, ...
Antimicrobial resistance in Enterobacteriaceae in Brazil: focus on beta-lactams and polymyxins
(Soc Brasileira Microbiologia, 2016)
uring the last 30 years there has been a dissemination of plasmid-mediated beta-lactamases in Enterobacteriaceae in Brazil. Extended spectrum beta-lactamases (ESBL) are widely disseminated in the hospital setting and are ...
In vitro susceptibility of Burkholderia cepacia complex isolates: Comparison of disk diffusion, Etest (R), agar dilution, and broth microdilution methods
(Elsevier Science Inc, 2016)
Broth microdilution, agar dilution, Etest (R) and disk diffusion techniques were compared to evaluate the susceptibility profile of 82 Bcc clinical isolates against six antimicrobials as recommended by CLSI. Broth microdilution ...
Rapid detection of bla(KPC) directly from surveillance rectal swabs by EasyQ KPC
(Elsevier Science Inc, 2018)
The performance of EasyQ KPC assay was evaluated for the first time for bla(KPC) detection directly from surveillance rectal swabs without broth enrichment. Using conventional polymerase chain reaction as gold standard ...
Detection of bla(VIM-7) in an extensively drug-resistant Pseudomonas aeruginosa isolate belonging to ST1284 in Brazil
(Elsevier Science Inc, 2017)
We described for the first time an extensively drug-resistant Pseudomonas aeruginosa isolate belonging to ST1284 carrying a plasmid-mediated bla(VIM-7) in Brazil. The bla(VIM-7) was harbored by an integron that also carried ...