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Combination Therapy with Methotrexate and Chloroquine in Rheumatoid Arthritis: A Multicenter Randomized Placebo-controlled Trial

Ferraz, Marcos Bosi [UNIFESP]; Pinheiro, Geraldo da Rocha Castelar [UNIFESP]; Helfenstein Junior, Milton[UNIFESP]; Albuquerque, E.; Rezende, C.; Roimicher, Luis; Brandao, Leticia de Campos [UNIFESP]; Silva, S. C.; Pinheiro, Geraldo da Rocha Castelar; Atra, Edgard [UNIFESP] (Scandinavian University Press, 1994-01-01)

To compare the efficacy of the combination therapy Methotrexate (MTX) and Chloroquine (CHLO) with MTX and Placebo (PLA) in the treatment of Rheumatoid Arthritis.A total of 82 patients with Rheumatoid Arthritis (RA), diagnosed ...

Lapatinib for treatment of advanced or metastasized breast cancer: systematic review

Riera, Rachel [UNIFESP]; Soarez, Patricia Coelho de [UNIFESP]; Puga, Maria Eduarda dos Santos [UNIFESP]; Ferraz, Marcos Bosi [UNIFESP] (Associacao Paulista Medicina, 2009-09-03)

CONTEXT AND OBJECTIVE: Around 16% to 20% of women with breast cancer have advanced, metastasized breast cancer. At this stage, the disease is treatable, but not curable. The objective here was to assess the effectiveness ...

Corticosteroids in patients with rheumatoid arthritis - Utility measurements for evaluating risks and benefits

Ferraz, Marcos Bosi [UNIFESP]; Quaresma, Marina Rodrigues [UNIFESP]; Goldsmith, C. H.; Bennett, K.; Atra, Edgard [UNIFESP] (Expansion Sci Francaise, 1994-04-01)

The purpose of this study was to use the utility approach to evaluate the risks and benefits of corticosteroid therapy in rheumatoid arthritis patients. The utility approach provides us with a quantitative measure of the ...

Health technology assessment: the process in Brazil

Abuleac, Fernanda Lessa [UNIFESP]; Ferraz, Marcos Bosi [UNIFESP] (Pan Amer Health Organization, 2017)

Objectives. To describe, analyze, and compare the opinions of decision makers involved in the health technology assessment (HTA) process in Brazil in 2011. Methods. A cross-sectional study was conducted using a structured ...