Now showing items 164-183 of 248

    • P2X(7) receptor and klotho expressions in diabetic nephropathy progression 

      Rodrigues, A. M. [UNIFESP]; Serralha, R. S. [UNIFESP]; Farias, C. [UNIFESP]; Punaro, Giovana Rita [UNIFESP]; Fernandes, M. J. S. [UNIFESP]; Higa, Elisa Mieko Suemitsu [UNIFESP] (Springer, 2018)
      Diabetes mellitus is characterized by increased levels of reactive oxygen species (ROS), leading to high levels of adenosine triphosphate (ATP) and the activation of purinergic receptors (P2X(7)), which results in cell ...
    • P2Y(12) receptor inhibition with prasugrel and ticagrelor in STEMI patients after fibrinolytic therapy: Analysis from the SAMPA randomized trial 

      Guimaraes, Leonardo de F. C. [UNIFESP]; Genereux, Philippe; Silveira, Diego [UNIFESP]; Pesaro, Antonio Eduardo; Falcao, Felipe [UNIFESP]; Barbosa, Bruno Robalinho C. [UNIFESP]; de Souza, Cristiano Freitas [UNIFESP]; Fonseca, Francisco A. H. [UNIFESP]; Rodrigues Alves, Claudia Maria [UNIFESP]; de Camargo Carvalho, Antonio Carlos [UNIFESP]; Stone, Gregg W.; Caixeta, Adriano [UNIFESP] (Elsevier Ireland Ltd, 2017)
      Background: A pharmacodynamic comparison between ticagrelor and prasugrel after fibrinolytic therapy has not yet been performed. Methods: In the single-center SAMPA trial, 50 consecutive STEMI patients previously treated ...
    • Paraneoplastic necrotizing myopathy - a case report 

      Ferraz, Alberto Pereira [UNIFESP]; José, Fábio Freire [UNIFESP] (Elsevier Science Inc, 2017)
    • Patellofemoral Cartilage Repair 

      Mestriner, Alexandre Barbieri [UNIFESP]; Ackermann, Jakob; Gomoll, Andreas H. (Springer, 2018)
      Purpose of Review This review provides an overview of well-established and newly developed cartilage repair techniques for cartilage defects in the patellofemoral joint (PFJ). An algorithm will be presented for approaching ...
    • Peripheral Vascular Resistance Impairment during Isometric Physical Exercise in Normotensive Offspring of Hypertensive Parents 

      Portela, Natalia; Amaral, Josaria Ferraz; de Carvalho Mira, Pedro Augusto; de Souza, Livia Victorino [UNIFESP]; Martinez, Daniel Godoy; Laterza, Mateus Camaroti (Arquivos Brasileiros Cardiologia, 2017)
      Background: A family history of hypertension is associated with vascular and autonomic abnormalities, as well as an impaired neurohemodynamic response to exercise. Objective: To test the hypothesis that normotensive ...
    • Phenotypic and genotypic detection of Candida albicans and Candida dubliniensis strains isolated from oral mucosa of AIDS pediatric patients 

      Liverio, Harisson Oliveira; Ruiz, Luciana da Silva; de Freitas, Roseli Santos; Nishikaku, Angela Satie [UNIFESP]; de Souza, Ana Clara; Paula, Claudete Rodrigues; Domaneschi, Carina (Inst Medicina Tropical Sao Paulo, 2017)
      The aim of this study was to assess a collection of yeasts to verify the presence of Candida dubliniensis among strains isolated from the oral mucosa of AIDS pediatric patients which were initially characterized as Candida ...
    • Photobiomodulation therapy protects skeletal muscle and improves muscular function of mdx mice in a dose-dependent manner through modulation of dystrophin 

      Albuquerque-Pontes, Gianna Moes; Casalechi, Heliodora Leao; Tomazoni, Shaiane Silva; Serra, Andrey Jorge; Ferreira, Cheila de Sousa Bacelar; Brito, Rodrigo Barbosa de Oliveira; Melo, Brunno Lemes de [UNIFESP]; Vanin, Adriane Aver; Monteiro, Kadma Karenina Damasceno Soares; Delle, Humberto; Frigo, Lucio; Marcos, Rodrigo Labat; Carvalho, Paulo de Tarso Camillo de; Leal-Junior, Ernesto Cesar Pinto (Springer London Ltd, 2018)
      This study aimed to analyze the protective effects of photobiomodulation therapy (PBMT) with combination of low-level laser therapy (LLLT) and light emitting diode therapy (LEDT) on skeletal muscle tissue to delay dystrophy ...
    • Physical exercises with free weights and elastic bands can improve body composition parameters in postmenopausal women: WEB protocol with a randomized controlled trial 

      Bittar, Simoni T.; Maeda, Sergio Setsuo [UNIFESP]; Marone, Marilia M. S.; Santili, Claudio (Lippincott Williams & Wilkins, 2016)
      Objective:The aim of this study was to assess the impact of a program of supervised physical exercises (WEB protocol) versus home-based exercises on body composition (lean mass and fat mass) in postmenopausal women.Methods:The ...
    • Physiological and clinical relevance of exercise ventilatory efficiency in COPD 

      Neder, J. Alberto; Berton, Danilo C.; Arbex, Flavio F. [UNIFESP]; Alencar, Maria Clara; Rocha, Alcides [UNIFESP]; Sperandio, Priscila A. [UNIFESP]; Palange, Paolo; O'Donnell, Denis E. (European Respiratory Soc Journals Ltd, 2017)
      Exercise ventilation (V'E) relative to carbon dioxide output (V'CO2) is particularly relevant to patients limited by the respiratory system, e.g. those with chronic obstructive pulmonary disease ( COPD). High V'E- V'CO2 ( ...
    • Physiological and sensory consequences of exercise oscillatory ventilation in heart failure-COPD 

      Rocha, Alcides [UNIFESP]; Arbex, Flavio Ferlin [UNIFESP]; Alencar, Maria Clara Noman de [UNIFESP]; Sperandio, Priscila Abreu [UNIFESP]; Hirai, Daniel Müller [UNIFESP]; Berton, Danilo C.; O'Donnell, Denis E.; Neder, Jose Alberto [UNIFESP] (Elsevier Ireland Ltd, 2016)
      Background: Exercise oscillatory ventilation (EOV) is associatedwith poor ventilatory efficiency and higher operating lung volumes in heart failure. These abnormalitiesmay be particularly deleterious to dyspnea and exercise ...
    • Plasma Metabolomics Biosignature According to HIV Stage of Infection, Pace of Disease Progression, Viremia Level and Immunological Response to Treatment 

      Scarpelini, Bruno [UNIFESP]; Zanoni, Michelle [UNIFESP]; Sucupira, Maria Cecília Araripe [UNIFESP]; Truong, Hong-Ha M.; Janini, Luiz Mário Ramos [UNIFESP]; Silva, Ismael Dale Cotrim Guerreiro da [UNIFESP]; Diaz, Ricardo Sobhie [UNIFESP] (Public Library Science, 2016)
      Background We evaluated plasma samples HIV-infected individuals with different phenotypic profile among five HIV-infected elite controllers and five rapid progressors after recent HIV infection and one year later and from ...
    • The polymyxin B-induced transcriptomic response of a clinical, multidrug-resistant Klebsiella pneumoniae involves multiple regulatory elements and intracellular targets 

      Ramos, Pablo Ivan Pereira; Custodio, Marlon Gregori Flores; Quispe Saji, Guadalupe del Rosario; Cardoso, Thiago; Silva, Gisele Lucchetti da; Braun, Graziela [UNIFESP]; Martins, Willames M. B. S. [UNIFESP]; Girardello, Raquel [UNIFESP]; Vasconcelos, Ana Tereza Ribeiro de; Fernandez, Elmer; Gales, Ana Cristina [UNIFESP]; Nicolas, Marisa Fabiana (Biomed Central Ltd, 2016)
      Background: The emergence of multidrug-resistant Klebsiella pneumoniae is a major public health concern. Many K. pneumoniae infections can only be treated when resorting to last-line drugs such as polymyxin B (PB). However, ...
    • A pooled analysis of nivolumab for the treatment of advanced non-small-cell lung cancer and the role of PD-L1 as a predictive biomarker 

      Aguiar, Pedro N., Jr. [UNIFESP]; Santoro, Ilka Lopes [UNIFESP]; Tadokoro, Hakaru [UNIFESP]; Lopes, Gilberto de Lima; Filardi, Bruno Andraus [UNIFESP]; Oliveira, Pedro; Castelo-Branco, Pedro; Mountzios, Giannis; de Mello, Ramon Andrade (Future Medicine Ltd, 2016)
      Background: Recent studies with nivolumab (a monoclonal antibody against programmed cell death 1 [PD-1] receptor) have shown promise non-small-cell lung cancer (NSCLC) treatment. Methods: To review available clinical trials ...
    • Posaconazole MIC Distributions for Aspergillus fumigatus Species Complex by Four Methods: Impact of cyp51A Mutations on Estimation of Epidemiological Cutoff Values 

      Espinel-Ingroff, A.; Turnidge, J.; Alastruey-Izquierdo, A.; Dannaoui, E.; Garcia-Effron, G.; Guinea, J.; Kidd, S.; Pelaez, T.; Sanguinetti, M.; Meletiadis, J.; Botterel, F.; Bustamante, B.; Chen, Y. -C.; Chakrabarti, A.; Chowdhary, A.; Chryssanthou, E.; Cordoba, S.; Gonzalez, G. M.; Guarro, J.; Johnson, E. M.; Kus, J. V.; Lass-Floerl, C.; Linares-Sicilia, M. J.; Martin-Mazuelos, E.; Negri, Clara Ezequiel [UNIFESP]; Pfaller, M. A.; Tortorano, A. M. (Amer Soc Microbiology, 2018)
      Estimating epidemiological cutoff endpoints (ECVs/ECOFFS) may be hindered by the overlap of MICs for mutant and nonmutant strains (strains harboring or not harboring mutations, respectively). Posaconazole MIC distributions ...
    • Postoperative persistent chronic pain: what do we know about prevention, risk factors, and treatment 

      Kraychete, Durval Campos; Sakata, Rioko Kimiko [UNIFESP]; Carvalho Lannes, Leticia de Oliveira; Bandeira, Igor Dorea; Sadatsune, Eduardo Jun [UNIFESP] (Elsevier Science Inc, 2016)
      Background and objectives: Postoperative persistent chronic pain (POCP) is a serious health problem, disabling, undermining the quality of life of affected patients. Although more studies and research have addressed the ...
    • The practice of intensive care in Latin America: a survey of academic intensivists 

      Castro, Ricardo; Nin, Nicolas; Rios, Fernando; Alegria, Leyla; Estenssoro, Elisa; Murias, Gaston; Friedman, Gilberto; Jibaja, Manuel; Ospina-Tascon, Gustavo; Hurtado, Javier; del Carmen Marin, Maria; Machado, Flavia R. [UNIFESP]; Cavalcanti, Alexandre Biasi; Dubin, Arnaldo; Azevedo, Luciano [UNIFESP]; Cecconi, Maurizio; Bakker, Jan; Hernandez, Glenn (Biomed Central Ltd, 2018)
      Background: Intensive care medicine is a relatively young discipline that has rapidly grown into a full-fledged medical subspecialty. Intensivists are responsible for managing an ever-increasing number of patients with ...
    • Predictive validity analysis of six reference equations for the 6-minute walk test in healthy Brazilian men: a cross-sectional study 

      Negreiros, Alexandher; Padula, Rosimeire Simprini; Bretas Bernardes, Rosane Andrea; de Moraes, Monica Vasconcelos; Pires, Raquel Simoni; Chiavegato, Luciana Dias [UNIFESP] (Associacao Brasileira Pesquisa Pos-Graduacao Fisioterapia-Abrapg-Ft, 2017)
      Background: The six-minute walk test (6MWT) is an important tool for evaluating functional capacity and exercise tolerance. The reference equations for the 6MWT in healthy subjects were established on the basis of American ...
    • Preferences of orthopedic surgeons for treating midshaft clavicle fracture in adults 

      de Oliveira Junior, Adilson Sanches; Roberto, Bruno Braga; Lenza, Mario; Pintan, Guilherme Figueiredo; Ejnisman, Benno [UNIFESP]; Schor, Breno; Carrera, Eduardo da Frota; Murachovsky, Joel (Inst Israelita Ensino & Pesquisa Albert Einstein, 2017)
      Objective: To determine the current clinical practice in Latin America for treating midshaft clavicle fractures, including surgical and non-surgical approaches. Methods: A cross-sectional study using a descriptive ...
    • Prevalence and correlates of non-adherence to immunosuppressants and to health behaviours in patients after kidney transplantation in Brazil - the ADHERE BRAZIL multicentre study: a cross-sectional study protocol 

      Sanders-Pinheiro, Helady; Basile Colugnati, Fernando Antonio; Marsicano, Elisa Oliveira; De Geest, Sabina; Pestana Medina, Jose Osmar [UNIFESP] (Biomed Central Ltd, 2018)
      Background: Non-adherence to immunosuppressive therapy is a prevalent risk factor for poor clinical and after kidney transplantation (KT), and has contributed to the lack of improvement in long-term graft survival over the ...
    • Prevalence of hepatitis delta virus among hemodialysis and renal transplant patients 

      Pierre, Alessandra Maria Mont'Alverne [UNIFESP]; Feldner, Ana Cristina de Castro Amaral [UNIFESP]; Carvalho Filho, Roberto Jose de [UNIFESP]; Lopes, Edmundo Pessoa de Almeida; Gouvea, Michele Soares Gomes; Pinho, Joao Renato Rebello; Carvente, Claudia Teresa [UNIFESP]; Emori, Christini Takemi [UNIFESP]; Silva, Genimari Arruda da [UNIFESP]; Ferraz, Maria Lucia Cardoso Gomes [UNIFESP] (Sage Publications Ltd, 2018)
      Introduction: Hepatitis B virus infection is an important cause of liver disease in hemodialysis patients and renal transplant recipients. Hepatitis Delta virus is a defective virus transmitted by the same route of hepatitis ...