Now showing items 155-174 of 248

    • Naturally Occurring Amino Acids in Helix 10 of the Thyroid Hormone Receptor Mediate Isoform-Specific TH Gene Regulation 

      Pinto, Vitor M. S. [UNIFESP]; Minakhina, Svetlana; Qiu, Shuiqing; Sidhaye, Aniket; Brotherton, Michael P.; Suhotliv, Amy; Wondisford, Fredric E. (Oxford Univ Press Inc, 2017)
      Thyroid hormone (TH) action is mediated by the products of two genes, TH receptor (THR) a (THRA) and THRb (THRB) that encode several closely related receptor isoforms with differing tissue distributions. The vast majority ...
    • Network Analysis to Risk Stratify Patients With Exercise Intolerance 

      Oldham, William M.; Oliveira, Rudolf Krawczenko Feitoza de [UNIFESP]; Wang, Rui-Sheng; Opotowsky, Alexander R.; Rubins, David M.; Hainer, Jon; Wertheim, Bradley M.; Alba, George A.; Choudhary, Gaurav; Tornyos, Adrienn; MacRae, Calum A.; Loscalzo, Joseph; Leopold, Jane A.; Waxman, Aaron B.; Olschewski, Horst; Kovacs, Gabor; Systrom, David M.; Maron, Bradley A. (Lippincott Williams & Wilkins, 2018)
      Rationale: Current methods assessing clinical risk because of exercise intolerance in patients with cardiopulmonary disease rely on a small subset of traditional variables. Alternative strategies incorporating the spectrum ...
    • Obesity, Bariatric Surgery, and Vitamin D 

      Borges, Joao Lindolfo C.; Miranda, Isabella Santiago de M.; Sarquis, Marta M. S.; Borba, Victoria; Maeda, Sergio Setsuo [UNIFESP]; Lazaretti-Castro, Marise [UNIFESP]; Blinkey, Neil (Elsevier Science Inc, 2018)
      The high prevalence of obesity is a worldwide problem associated with multiple comorbidities, including cardiovascular diseases. Vitamin D deficiency with secondary hyperparathyroidism is common in obese individuals and ...
    • Obstructive sleep apnea knowledge and attitudes among recent medical graduates training in Ecuador 

      Cherrez-Ojeda, Ivan; Carlos Calderon, Juan; Fernandez Garcia, Andrea; Jeffe, Donna B.; Santoro, Ilka [UNIFESP]; Vanegas, Emanuel; Cherrez, Annia; Cano, Jose; Betancourt, Freddy; Simancas-Racines, Daniel (Biomed Central Ltd, 2018)
      Background: We aimed to assess recent Latin American medical school graduates' knowledge and attitudes about OSA and examine whether their knowledge and attitudes about OSA differed from practicing physicians. Methods: ...
    • Open-Label, Randomized Study of Transition From Tacrolimus to Sirolimus Immunosuppression in Renal Allograft Recipients 

      Tedesco-Silva, Helio [UNIFESP]; Peddi, V. Ram; Sanchez-Fructuoso, Ana; Marder, Brad A.; Russ, Graeme R.; Diekmann, Fritz; Flynn, Alison; Hahn, Carolyn M.; Li, Huihua; Tortorici, Michael A.; Schulman, Seth L. (Lippincott Williams & Wilkins, 2016)
      Background. Calcineurin inhibitor-associated nephrotoxicity and other adverse events have prompted efforts to minimize/eliminate calcineurin inhibitor use in kidney transplant recipients. Methods. This open-label, randomized, ...
    • Opinions of Brazilian resuscitation instructors regarding resuscitation in the delivery room of extremely preterm newborns 

      Ambrosio, Cristiane Ribeiro [UNIFESP]; Almeida, Maria Fernanda Branco de [UNIFESP]; Guinsburg, Ruth [UNIFESP] (Soc Brasil Pediatria, 2016)
      Objective: To describe the opinions of pediatricians who teach resuscitation in Brazil on initiating and limiting the delivery room resuscitation of extremely preterm infants. Method: Cross-sectional study with electronic ...
    • Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration 

      Ferrara, Daniela; Silver, Rachel E.; Louzada, Ricardo N.; Novais, Eduardo A. [UNIFESP]; Collins, Giliann K.; Seddon, Johanna M. (Assoc Research Vision Ophthalmology Inc, 2017)
      PURPOSE. Age-related macular degeneration (AMD) is a progressive disease with multifactorial etiology. There is a need to identify clinical features that are harbingers of advanced disease. We evaluated morphologic features ...
    • Oral health care in the Xingu Indigenous Park, Brazil, from 2004 to 2013: an analysis based on evaluation indicators 

      Lemos, Pablo Natanael [UNIFESP]; Rodrigues, Douglas Antonio [UNIFESP]; Frazao, Paulo; Hirooka, Lucila Brandao; Guisilini, Alana Cristina; Narvai, Paulo Capel (Cadernos Saude Publica, 2018)
      In 2011, the Brazilian National Oral Health Policy redefined its model of care for indigenous peoples, recommending the use of epidemiology and follow-up of the impact of activities using adequate indicators. The current ...
    • Orthopaedics injuries in male professional football players in Brazil: a prospective comparison between two divisions 

      Arliani, Gustavo Goncalves [UNIFESP]; Schmidt Lara, Paulo Henrique [UNIFESP]; Astur, Diego Costa [UNIFESP]; Pedrinelli, Andre [UNIFESP]; Pagura, Jorge Roberto [UNIFESP]; Cohen, Moises [UNIFESP] (Cic Edizioni Int, 2017)
      Background: Football is a high-speed contact sport and the risk of injury is high. The objective of this study was to compare the two main divisions (A1 and A2) of the Sao Paulo Football Championship and to perform a ...
    • P2X(7) receptor and klotho expressions in diabetic nephropathy progression 

      Rodrigues, A. M. [UNIFESP]; Serralha, R. S. [UNIFESP]; Farias, C. [UNIFESP]; Punaro, Giovana Rita [UNIFESP]; Fernandes, M. J. S. [UNIFESP]; Higa, Elisa Mieko Suemitsu [UNIFESP] (Springer, 2018)
      Diabetes mellitus is characterized by increased levels of reactive oxygen species (ROS), leading to high levels of adenosine triphosphate (ATP) and the activation of purinergic receptors (P2X(7)), which results in cell ...
    • P2Y(12) receptor inhibition with prasugrel and ticagrelor in STEMI patients after fibrinolytic therapy: Analysis from the SAMPA randomized trial 

      Guimaraes, Leonardo de F. C. [UNIFESP]; Genereux, Philippe; Silveira, Diego [UNIFESP]; Pesaro, Antonio Eduardo; Falcao, Felipe [UNIFESP]; Barbosa, Bruno Robalinho C. [UNIFESP]; de Souza, Cristiano Freitas [UNIFESP]; Fonseca, Francisco A. H. [UNIFESP]; Rodrigues Alves, Claudia Maria [UNIFESP]; de Camargo Carvalho, Antonio Carlos [UNIFESP]; Stone, Gregg W.; Caixeta, Adriano [UNIFESP] (Elsevier Ireland Ltd, 2017)
      Background: A pharmacodynamic comparison between ticagrelor and prasugrel after fibrinolytic therapy has not yet been performed. Methods: In the single-center SAMPA trial, 50 consecutive STEMI patients previously treated ...
    • Paraneoplastic necrotizing myopathy - a case report 

      Ferraz, Alberto Pereira [UNIFESP]; José, Fábio Freire [UNIFESP] (Elsevier Science Inc, 2017)
    • Patellofemoral Cartilage Repair 

      Mestriner, Alexandre Barbieri [UNIFESP]; Ackermann, Jakob; Gomoll, Andreas H. (Springer, 2018)
      Purpose of Review This review provides an overview of well-established and newly developed cartilage repair techniques for cartilage defects in the patellofemoral joint (PFJ). An algorithm will be presented for approaching ...
    • Peripheral Vascular Resistance Impairment during Isometric Physical Exercise in Normotensive Offspring of Hypertensive Parents 

      Portela, Natalia; Amaral, Josaria Ferraz; de Carvalho Mira, Pedro Augusto; de Souza, Livia Victorino [UNIFESP]; Martinez, Daniel Godoy; Laterza, Mateus Camaroti (Arquivos Brasileiros Cardiologia, 2017)
      Background: A family history of hypertension is associated with vascular and autonomic abnormalities, as well as an impaired neurohemodynamic response to exercise. Objective: To test the hypothesis that normotensive ...
    • Phenotypic and genotypic detection of Candida albicans and Candida dubliniensis strains isolated from oral mucosa of AIDS pediatric patients 

      Liverio, Harisson Oliveira; Ruiz, Luciana da Silva; de Freitas, Roseli Santos; Nishikaku, Angela Satie [UNIFESP]; de Souza, Ana Clara; Paula, Claudete Rodrigues; Domaneschi, Carina (Inst Medicina Tropical Sao Paulo, 2017)
      The aim of this study was to assess a collection of yeasts to verify the presence of Candida dubliniensis among strains isolated from the oral mucosa of AIDS pediatric patients which were initially characterized as Candida ...
    • Photobiomodulation therapy protects skeletal muscle and improves muscular function of mdx mice in a dose-dependent manner through modulation of dystrophin 

      Albuquerque-Pontes, Gianna Moes; Casalechi, Heliodora Leao; Tomazoni, Shaiane Silva; Serra, Andrey Jorge; Ferreira, Cheila de Sousa Bacelar; Brito, Rodrigo Barbosa de Oliveira; Melo, Brunno Lemes de [UNIFESP]; Vanin, Adriane Aver; Monteiro, Kadma Karenina Damasceno Soares; Delle, Humberto; Frigo, Lucio; Marcos, Rodrigo Labat; Carvalho, Paulo de Tarso Camillo de; Leal-Junior, Ernesto Cesar Pinto (Springer London Ltd, 2018)
      This study aimed to analyze the protective effects of photobiomodulation therapy (PBMT) with combination of low-level laser therapy (LLLT) and light emitting diode therapy (LEDT) on skeletal muscle tissue to delay dystrophy ...
    • Physical exercises with free weights and elastic bands can improve body composition parameters in postmenopausal women: WEB protocol with a randomized controlled trial 

      Bittar, Simoni T.; Maeda, Sergio Setsuo [UNIFESP]; Marone, Marilia M. S.; Santili, Claudio (Lippincott Williams & Wilkins, 2016)
      Objective:The aim of this study was to assess the impact of a program of supervised physical exercises (WEB protocol) versus home-based exercises on body composition (lean mass and fat mass) in postmenopausal women.Methods:The ...
    • Physiological and clinical relevance of exercise ventilatory efficiency in COPD 

      Neder, J. Alberto; Berton, Danilo C.; Arbex, Flavio F. [UNIFESP]; Alencar, Maria Clara; Rocha, Alcides [UNIFESP]; Sperandio, Priscila A. [UNIFESP]; Palange, Paolo; O'Donnell, Denis E. (European Respiratory Soc Journals Ltd, 2017)
      Exercise ventilation (V'E) relative to carbon dioxide output (V'CO2) is particularly relevant to patients limited by the respiratory system, e.g. those with chronic obstructive pulmonary disease ( COPD). High V'E- V'CO2 ( ...
    • Physiological and sensory consequences of exercise oscillatory ventilation in heart failure-COPD 

      Rocha, Alcides [UNIFESP]; Arbex, Flavio Ferlin [UNIFESP]; Alencar, Maria Clara Noman de [UNIFESP]; Sperandio, Priscila Abreu [UNIFESP]; Hirai, Daniel Müller [UNIFESP]; Berton, Danilo C.; O'Donnell, Denis E.; Neder, Jose Alberto [UNIFESP] (Elsevier Ireland Ltd, 2016)
      Background: Exercise oscillatory ventilation (EOV) is associatedwith poor ventilatory efficiency and higher operating lung volumes in heart failure. These abnormalitiesmay be particularly deleterious to dyspnea and exercise ...
    • Plasma Metabolomics Biosignature According to HIV Stage of Infection, Pace of Disease Progression, Viremia Level and Immunological Response to Treatment 

      Scarpelini, Bruno [UNIFESP]; Zanoni, Michelle [UNIFESP]; Sucupira, Maria Cecília Araripe [UNIFESP]; Truong, Hong-Ha M.; Janini, Luiz Mário Ramos [UNIFESP]; Silva, Ismael Dale Cotrim Guerreiro da [UNIFESP]; Diaz, Ricardo Sobhie [UNIFESP] (Public Library Science, 2016)
      Background We evaluated plasma samples HIV-infected individuals with different phenotypic profile among five HIV-infected elite controllers and five rapid progressors after recent HIV infection and one year later and from ...