Now showing items 192-211 of 248

    • A randomised, double-blind, trial of the safety and efficacy of omarigliptin (a once-weekly DPP-4 inhibitor) in subjects with type 2 diabetes and renal impairment 

      Chacra, Antonio [UNIFESP]; Gantz, Ira; Mendizabal, Geraldine; Durlach, Lucila; O'Neill, Edward A.; Zimmer, Zachary; Suryawanshi, Shailaja; Engel, Samuel S.; Lai, Eseng (Wiley, 2017)
      Aims: To assess the safety and efficacy of omarigliptin in subjects with type 2 diabetes mellitus (T2DM) and chronic renal impairment (RI). Methods: Patients with T2DM with moderate RI (estimated glomerular filtration rate ...
    • Randomized prospective study of three different techniques for ultrasound-guided axillary brachial plexus block 

      Cunha Ferraro, Leonardo Henirque [UNIFESP]; Takeda, Alexandre [UNIFESP]; Castello Branco de Sousa, Paulo Cesar [UNIFESP]; Gomes Mehlmann, Fernanda Moreira [UNIFESP]; Mitsunaga Junior, Jorge Kiyoshi [UNIFESP]; dos Reis Falcao, Luiz Fernando [UNIFESP] (Elsevier Science Inc, 2018)
      Introduction: Randomized prospective study comparing two perivascular techniques with the perineural technique for ultrasound-guided axillary brachial plexus block (US-ABPB). The primary objective was to verify if these ...
    • Rapid detection of bla(KPC) directly from surveillance rectal swabs by EasyQ KPC 

      Ramos, Ana Carolina [UNIFESP]; Schandert, Lygia [UNIFESP]; Carvalhaes, Cecilia Godoy [UNIFESP]; Martins, Rafael Affini [UNIFESP]; Cappellano, Paola [UNIFESP]; Machado, Flavia Ribeiro [UNIFESP]; Gales, Ana Cristina [UNIFESP] (Elsevier Science Inc, 2018)
      The performance of EasyQ KPC assay was evaluated for the first time for bla(KPC) detection directly from surveillance rectal swabs without broth enrichment. Using conventional polymerase chain reaction as gold standard ...
    • Recent Advances in New Discovered Molecular Targets in Testicular Germ Cell Tumors 

      Carita, Amanda C. [UNIFESP]; Eloy, Josimar O.; Chorilli, Marlus; Lee, Robert J.; Leonardi, Gislaine Ricci (Bentham Science Publ Ltd, 2018)
      The cutaneous route is attractive for the delivery of drugs in the treatment of a wide variety of diseases. However the stratum corneum (SC) is an effective barrier that hampers skin penetration. Within this context, ...
    • Recommendations for the pharmacological treatment of COPD: questions and answers 

      Arrabal Fernandes, Frederico Leon; Cukier, Alberto; Camelier, Aquiles Assuncao; Fritscher, Carlos Cezar; da Costa, Claudia Henrique; Barros Pereira, Eanes Delgado; Godoy, Irma; Delfini Cancado, Jose Eduardo; Romaldini, Jose Gustavo; Chatkin, Jose Miguel; Jardim, Jose Roberto [UNIFESP]; Rabahi, Marcelo Fouad; Nieves Maiorano de Nucci, Maria Cecilia; Uchoa Sales, Maria da Penha; Cruz de Oliveira Castellano, Maria Vera; Aide, Miguel Abidon; Zimermann Teixeira, Paulo Jose; Maciel, Renato; Correa, Ricardo de Amorim; Stirbulov, Roberto; Athanazio, Rodrigo Abensur; Russo, Rodrigo; Minamoto, Suzana Tanni; Cavalcanti Lundgren, Fernando Luiz (Soc Brasileira Pneumologia Tisiologia, 2017)
      The treatment of COPD has become increasingly effective. Measures that range from behavioral changes, reduction in exposure to risk factors, education about the disease and its course, rehabilitation, oxygen therapy, ...
    • Reduced schedules of 4CMenB vaccine in infants and catch-up series in children: Immunogenicity and safety results from a randomised open-label phase 3b trial 

      Martinon-Torres, Federico; Safadi, Marco Aurelio P.; Carmona Martinez, Alfonso; Infante Marquez, Pilar; Tejedor Torres, Juan Carlos; Weckx, Lily Yin [UNIFESP]; Moreira Junior, Edson Duarte; Mensi, Ilhem; Calabresi, Marco; Toneatto, Daniela (Elsevier Sci Ltd, 2017)
      Background: This study evaluated the immunogenicity and safety of a licensed meningococcal serogroup B vaccine (4CMenB) administered alone according to reduced schedules in infants or catch-up series in children. Methods: ...
    • Regional differences in the prevalence of diabetic retinopathy: a multi center study in Brazil 

      Drummond, Karla Rezende Guerra; Malerbi, Fernando Korn [UNIFESP]; Morales, Paulo Henrique [UNIFESP]; Mattos, Tessa Cerqueira Lemos; Pinheiro, Andre Araujo; Mallmann, Felipe; Perez, Ricardo Vessoni; Leal, Franz Schubert Lopes; Melo, Laura Gomes Nunes de; Gomes, Marilia Brito (Biomed Central Ltd, 2018)
      Background: Diabetic retinopathy has a significant impact in every healthcare system. Despite that fact, there are few accurate estimates in the prevalence of DR in Brazil's different geographic regions, particularly ...
    • Relation among 25(oh)d, aquatic exercises, and multifunctional fitness on functional performance of elderly women from the community 

      Nascimento, Neide Aparecida Perigo [UNIFESP]; Moreira, Patricia Ferreira do Prado [UNIFESP]; Marin, Rosangela Villa [UNIFESP]; Moreira, Linda Denise Fernandes [UNIFESP]; Lazaretti-Castro, Marise [UNIFESP]; Santos, Carlos André Freitas dos [UNIFESP]; Almada Filho, Clineu de Mello [UNIFESP]; Cendoroglo, Maysa Seabra [UNIFESP] (Springer France, 2016)
      Objectives The aim of this study was to investigate if there is a relation among 25(OH)D, aquatic training, and multifunctional fitness on functional performance of elderly woman from the community. Design: Cross-sectional ...
    • Relation of asymmetrical dimethylarginine levels with renal outcomes in hypertensive patients with and without type 2 diabetes mellitus 

      Triches, Cristina B. [UNIFESP]; Quinto, Marie [UNIFESP]; Mayer, Saurus [UNIFESP]; Batista, Marcelo [UNIFESP]; Zanella, Maria Teresa [UNIFESP] (Elsevier Science Inc, 2018)
      Aim: The aim of the study was to evaluate the association between high plasma ADMA levels, a biomarker of endothelial dysfunction, with the progression of albuminuria and chronic kidney disease (CKD) in hypertensive patients, ...
    • Renal transplantation in human immunodeficiency virus-infected recipients: a case-control study from the Brazilian experience 

      Vicari, A. R.; Spuldaro, F.; Freitas, Tainá Veras de Sandes [UNIFESP]; Cristelli, Marina Pontello [UNIFESP]; Requiao-Moura, L. R.; Reusing, J. O.; Pierrotti, L. C.; Oliveira, M. L.; Girao, C. M.; Gadonski, G.; Kroth, L. V.; Deboni, L. M.; Ferreira, G. F.; Tedesco-Silva, Helio [UNIFESP]; Esmeraldo, R.; David-Neto, E.; Saitovitch, D.; Keitel, E.; Garcia, V. D.; Pacheco-Silva, A.; Pestana, Jose Osmar Medina [UNIFESP]; Manfro, R. C. (Wiley-Blackwell, 2016)
      BackgroundHighly active antiretroviral therapy has turned human immunodeficiency virus (HIV)-infected patients with end-stage renal disease into suitable candidates for renal transplantation. We present the Brazilian ...
    • Ribavirin induces widespread accumulation of IMP dehydrogenase into rods/rings structures in multiple major mouse organs 

      Keppeke, Gerson D; Calise, S. John; Chan, Edward K.L.; Andrade, Luis Eduardo C. (Mike Bray, 2019-02)
    • The risk of dengue for non-immune foreign visitors to the 2016 summer olympic games in Rio de Janeiro, Brazil 

      Ximenes, Raphael; Amaku, Marcos; Lopez, Luis Fernandez; Coutinho, Francisco Antonio Bezerra; Burattini, Marcelo Nascimento [UNIFESP]; Greenhalgh, David; Wilder-Smith, Annelies; Struchiner, Claudio Jose; Massad, Eduardo (Biomed Central Ltd, 2016)
      Background: Rio de Janeiro in Brazil will host the Summer Olympic Games in 2016. About 400,000 non-immune foreign tourists are expected to attend the games. As Brazil is the country with the highest number of dengue cases ...
    • Risk stratification of patients undergoing medical therapy after coronary angiography 

      Bettinger, Nicolas; Palmerini, Tullio; Caixeta, Adriano [UNIFESP]; Dressler, Ovidiu; Litherland, Claire; Francese, Dominic P.; Giustino, Gennaro; Mehran, Roxana; Leon, Martin B.; Stone, Gregg W.; Genereux, Philippe (Oxford Univ Press, 2016)
      Aim We sought to investigate the prognostic impact of the SYNTAX (Synergy between PCI with TAXUS and Cardiac Surgery) score (SS) on 1-year clinical outcomes in patients with non-ST-segment elevation acute coronary syndromes ...
    • The role of digital health in supporting the achievement of the Sustainable Development Goals (SDGs) 

      Novillo-Ortiz, David; Marin, Heimar de Fatima [UNIFESP]; Saigi-Rubio, Francesc (Elsevier Ireland Ltd, 2018)
    • Role of low-level laser therapy on the cardiac remodeling after myocardial infarction: A systematic review of experimental studies 

      Carlos, Fernando Pereira; Gradinetti, Vanessa; Manchini, Martha; Camillo de Carvalho, Paulo de Tarso; Silva, Jose Antonio, Jr.; Costa Girardi, Adriana Castello; Pinto Leal-Junior, Ernesto Cesar; Bocalini, Danilo Sales; Vieira, Stella [UNIFESP]; Antonio, Ednei Luiz [UNIFESP]; Tucci, Paulo [UNIFESP]; Serra, Andrey Jorge (Pergamon-Elsevier Science Ltd, 2016)
      Aims: We systematically reviewed the role of low-level laser therapy (LLLT) in cardiac remodeling after myocardial infarction. Main methods: Literatures were systematically searched in several electronic databases. We ...
    • The role of PD-L1 expression as a predictive biomarker in advanced non-small-cell lung cancer: a network meta-analysis 

      Aguiar Junior, Pedro [UNIFESP]; Santoro, Ilka Lopes [UNIFESP]; Tadokoro, Hakaru [UNIFESP]; Lopes, Gilberto de Lima; Filardi, Bruno Andraus [UNIFESP]; Oliveira, Pedro; Mountzios, Giannis; de Mello, Ramon Andrade (Future Medicine Ltd, 2016)
      Background: Tumor programmed death ligand one (PD-L1) expression has been studied in several trials in non-small-cell lung cancer. Methods: We assessed the potential role of PD-L1 expression according to Cochrane Collaboration's ...
    • Rotavirus genotypes as etiological agents of diarrhoea in general populations of two geographic regions of Brazil 

      Leite, Marcel [UNIFESP]; Compagnoli Carmona, Rita de Cassia; Carraro, Emerson; Aranha Watanabe, Aripuana Sakurada [UNIFESP]; Hernandes Granato, Celso Francisco [UNIFESP] (Inst Medicina Tropical Sao Paulo, 2017)
      Rotavirus is the main global cause of severe childhood diarrhoea among children. In 2006, Rotarix r (G1P[8]) was introduced into Brazil's National Immunization Program. The vaccine coverage rate was 84.4% in 2009. Evidences ...
    • Scleroderma in children - a report of 11 cases 

      Goldenberg, José [UNIFESP]; Duarte, Angela Luzia Branco Pinto [UNIFESP]; Hilário, Maria Odete Esteves [UNIFESP]; Atra, Edgard [UNIFESP]; Naspitz, Charles Kirov [UNIFESP] (Expansion Sci Francaise, 1993-02-01)
      Scleroderma is uncommon in children and adolescents. Eighty-four cases have been reported. With reference to a new series of 11 cases, the clinical features and course of the disease are described. Prognosis was good. There ...
    • Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor 

      Mathez, Andreia Latanza Gomes [UNIFESP]; Moroto, Debora [UNIFESP]; Dib, Sergio Atala [UNIFESP]; Sa, Joao Roberto de [UNIFESP] (Biomed Central Ltd, 2016)
      A rare sign of some malignant tumors is a sudden eruption of multiple seborrheic keratoses called Leser-Trelat sign. Overproduction of insulin-like growth factor-2 (IGF2) or its precursor is the main mechanism related to ...
    • Sensory-motor training versus resistance training among patients with knee osteoarthritis: randomized single-blind controlled trial 

      Gomiero, Aline Bassoli [UNIFESP]; Kayo, Andrea [UNIFESP]; Abraao, Marcelo [UNIFESP]; Peccin, Maria Stella [UNIFESP]; Grande, Antonio Jose; Trevisani, Virginia Fernandes [UNIFESP] (Associacao Paulista Medicina, 2018)
      BACKGROUND: Osteoarthritis of the knee is defined as a progressive disease of the synovial joints and is characterized by failure of joint damage repair. The objective here was to compare the effectiveness of sensory-motor ...