Determinação eletroanalítica em plantas medicinais e fitoterápicos: uma revisão
Data
2023
Tipo
Trabalho de conclusão de curso
Título da Revista
ISSN da Revista
Título de Volume
Resumo
As plantas medicinais reúnem muitas substâncias que podem agir em conjunto,
sendo um dos motivos que tornam muito complexa a padronização e o controle de
qualidade destes fitoterápicos. As técnicas eletroanalíticas aparecem com uma
alternativa para a determinação de compostos orgânicos de interesse, pois além de
simples e de baixo custo oferecem a possibilidade de determinar a concentração de
compostos diretamente na amostra e sem pré-tratamentos laboriosos. No entanto, no
que diz respeito ao estudo eletroanalítico de plantas medicinais e fitoterápicos, poucos
trabalhos são encontrados na literatura. Desta forma o objetivo deste trabalho foi fazer
uma revisão da literatura e uma avaliação crítica (qualitativa e quantitativa) sobre a
determinação eletroanalítica do princípio ativo de plantas medicinais e fitoterápicos
como a Passiflora (maracujá), Mikania Glomerata (Guaco) e a Valeriana Officinalis
(Valeriana selvagem).
A partir dessa revisão bibliográfica foi possível observar que a determinação
eletroanalítica provou ser uma abordagem valiosa no estudo de plantas medicinais e
fitoterápicos. Técnicas de voltametria têm sido utilizadas como alternativa para
determinação de compostos ativos, fornecendo informações importantes sobre a
composição química dessas plantas e a quantificação de seus princípios ativos. Esses
avanços contribuem para o desenvolvimento de medicamentos fitoterápicos seguros
e de qualidade para uso na medicina tradicional e complementar. Portanto, as técnicas
voltamétricas mostraram-se uma alternativa para determinação dos princípios ativos
selecionados por apresentarem alta sensibilidade e repetibilidade de resultados, além
de ser uma técnica barata e simples.
Medicinal plants bring together many substances that can act together, which is one of the reasons that make the standardization and quality control of these herbal medicines very complex. Electroanalytical techniques appear as an alternative for determining organic compounds of interest, as they are simple and low-cost and offer the possibility of determining the concentration of compounds directly in the sample and without laborious pre-treatments. However, with regard to the electroanalytical study of medicinal plants and herbal medicines, few works are found in the literature. Therefore, the objective of this work was to review the literature and make a critical assessment (qualitative and quantitative) on the electroanalytical determination of the active ingredient of medicinal plants and herbal medicines such as Passiflora (passion fruit), Mikania Glomerata (Guaco) and Valeriana Officinalis ( Wild valerian). From this literature review it was possible to observe that electroanalytical determination proved to be a valuable approach in the study of medicinal plants and herbal medicines. Voltammetry techniques have been used as an alternative for determining active compounds, providing important information about the chemical composition of these plants and the quantification of their active principles. These advances contribute to the development of safe and quality herbal medicines for use in traditional and complementary medicine. Therefore, voltammetric techniques proved to be an alternative for determining the selected active ingredients as they present high sensitivity and repeatability of results, in addition to being a cheap and simple technique.
Medicinal plants bring together many substances that can act together, which is one of the reasons that make the standardization and quality control of these herbal medicines very complex. Electroanalytical techniques appear as an alternative for determining organic compounds of interest, as they are simple and low-cost and offer the possibility of determining the concentration of compounds directly in the sample and without laborious pre-treatments. However, with regard to the electroanalytical study of medicinal plants and herbal medicines, few works are found in the literature. Therefore, the objective of this work was to review the literature and make a critical assessment (qualitative and quantitative) on the electroanalytical determination of the active ingredient of medicinal plants and herbal medicines such as Passiflora (passion fruit), Mikania Glomerata (Guaco) and Valeriana Officinalis ( Wild valerian). From this literature review it was possible to observe that electroanalytical determination proved to be a valuable approach in the study of medicinal plants and herbal medicines. Voltammetry techniques have been used as an alternative for determining active compounds, providing important information about the chemical composition of these plants and the quantification of their active principles. These advances contribute to the development of safe and quality herbal medicines for use in traditional and complementary medicine. Therefore, voltammetric techniques proved to be an alternative for determining the selected active ingredients as they present high sensitivity and repeatability of results, in addition to being a cheap and simple technique.