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dc.contributor.authorCarmo, Mirian Silva do [UNIFESP]
dc.contributor.authorInoue, Fernanda [UNIFESP]
dc.contributor.authorAndrade, Soraya Sgambatti [UNIFESP]
dc.contributor.authorPaschoal, Luiz [UNIFESP]
dc.contributor.authorSilva, Fernanda M. [UNIFESP]
dc.contributor.authorOliveira, Vitor [UNIFESP]
dc.contributor.authorPignatari, Antonio Carlos Campos [UNIFESP]
dc.date.accessioned2015-06-14T13:43:16Z
dc.date.available2015-06-14T13:43:16Z
dc.date.issued2011-10-01
dc.identifierhttp://dx.doi.org/10.1590/S0100-879X2011007500114
dc.identifier.citationBrazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 44, n. 10, p. 1013-1017, 2011.
dc.identifier.issn0100-879X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/6625
dc.description.abstractAn increased incidence of nosocomial and community-acquired infections caused by methicillin-resistant Staphylococcus aureus (MRSA) has been observed worldwide. The molecular characterization of MRSA has played an important role in demonstrating the existence of internationally disseminated clones. The use of molecular biology methods in the surveillance programs has enabled the tracking of MRSA spread within and among hospitals. These data are useful to alert nosocomial infection control programs about the potential introduction of these epidemic clones in their areas. Four MRSA blood culture isolates from patients hospitalized at two hospitals in the city of São Paulo, Brazil, were analyzed; one of them was community acquired. The isolates were characterized as SCCmec, mecA and PVL by PCR, pulsed-field gel electrophoresis (PFGE) profile and molecular sequence typing (MLST) genotyping. The isolates presented type IV SCCmec, and none proved to be positive for PVL. The isolates showed a PFGE profile similar to the pediatric clone. MLST genotyping demonstrated that the isolates belonged to clonal complex 5 (CC5), showing a new yqiL allele gene, resulting in a new sequence typing (ST) (1176). Our results showed that strains of MRSA carrying a new ST are emerging in community and nosocomial infections, including bacteremia, in São Paulo, Brazil.en
dc.format.extent1013-1017
dc.language.isoeng
dc.publisherAssociação Brasileira de Divulgação Científica
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.rightsAcesso aberto
dc.subjectMethicillin-resistant Staphylococcus aureusen
dc.subjectMolecular sequence typingen
dc.subjectResistanceen
dc.subjectMolecular typingen
dc.titleNew multilocus sequence typing of MRSA in São Paulo, Brazilen
dc.typeArtigo
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionCentro Universitário Fundação Instituto de Ensino para Osasco
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Departamento de Doenças Infecciosas e Parasitárias Laboratório Especial de Microbiologia Clínica
dc.description.affiliationCentro Universitário Fundação Instituto de Ensino para Osasco
dc.description.affiliationUnifespUNIFESP, Depto. de Doenças Infecciosas e Parasitárias Laboratório Especial de Microbiologia Clínica
dc.identifier.fileS0100-879X2011001000006.pdf
dc.identifier.scieloS0100-879X2011001000006
dc.identifier.doi10.1590/S0100-879X2011007500114
dc.description.sourceSciELO
dc.identifier.wosWOS:000295721600006


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