Plakilactone J: Structure and absolute configuration

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Date
2022-11-12Author
Batista, Andrea Nastri de Luca
Brito, Mateus de Freitas
Batista Junior, João Marcos [UNIFESP]
Valverde, Alessandra Leda
Type
ArtigoIs part of
Tetrahedron LettersDOI
10.1016/j.tetlet.2022.154241Metadata
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The chemical investigation of the Brazilian marine sponge Plakortis angulospiculatus led to the isolation of the new peroxide-derived polyketide plakilactone J (1). The structure of (-)-1 was established by means of HRMS and NMR analysis, while its absolute configuration was unambiguously determined as (4R,6R) by vibrational circular dichroism spectroscopy and density functional theory calculations.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Collections
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