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Didanosine-Loaded Chitosan Microspheres: Optimization of Fabrication Process
(Colegio Farmaceuticos Provincia De Buenos Aires, 2011-06-01)
Didanosine (ddI) is an important drug in the AIDS therapy. However, to overcome the instability of ddI in acid medium, the tablets have a large amount of buffer that can lead to side effects such as diarrhea and kidney ...