Now showing items 955-974 of 1033

    • Synthesis and characterization of aminolevulinic acid gold nanoparticles: Photo and sonosensitizer agent for atherosclerosis 

      Goncalves, Karina de Oliveira [UNIFESP]; Vieira, Daniel Perez [UNIFESP]; Courrol, Lilia Coronato [UNIFESP] (Elsevier Science Bv, 2018)
      Photodynamic and sonodynamic therapies (PDT and SDT, respectively) are emerging as new atherosclerosis treatments. The subsequent generation of free radicals by activated photo and sonosensitizers can lead to apoptotic ...

    • Synthesis and characterization of mesoporous NiO2/ZrO2-CeO2 catalysts for total methane conversion 

      Bacani, R.; Toscani, L. M.; Martins, T. S. [UNIFESP]; Fantini, M. C. A.; Lamas, D. G.; Larrondo, S. A. (Elsevier Sci Ltd, 2017)
      This work reports the synthesis and characterization of mesoporous NiO/ZrO2-CeO2 composites. These materials are still being developed due to their excellent morphological and structural properties, especially for solid ...

    • Synthesis and Characterization of Methylene Blue-Containing Silica-Coated Magnetic Nanoparticles for Photodynamic Therapy 

      Fudimura, Karina Amancio [UNIFESP]; Seabra, Amedea Barozzi [UNIFESP]; Santos, Marconi da Cruz [UNIFESP]; Haddad, Paula Silvia [UNIFESP] (Amer Scientific Publishers, 2017)
      Superparamagnetic iron oxide nanoparticles (SPIONs), with appropriate surface coating, are commonly used for biomedical applications such as photodynamic therapy (PDT). This work describes the preparation and characterization ...

    • Synthesis and trypanocidal activity of a library of 4-substituted 2-(1H-pyrrolo[3,2-c]pyridin-2-yl)propan-2-ols 

      Balfour, Michael N. [UNIFESP]; Franco, Caio H.; Moraes, Carolina B.; Freitas-Junior, Lucio H.; Stefani, Helio A. [UNIFESP] (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)
      A library of 16 4-substituted 2-(1H-pyrrolo[3,2-c]pyridin-2-yl)propan-2-ols 17-32 has been synthesized for use in biological testing against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease. The ...

    • Synthesis of Diiodo-Functionalized Benzo[b] furans via Electrophilic Iodocyclization 

      Frota, Carlise; Rossini, Allan F. C. [UNIFESP]; Casagrande, Gleison A.; Pizzuti, Lucas; Raminelli, Cristiano [UNIFESP] (Soc Brasileira Quimica, 2017)
      An electrophilic iodocyclization reaction involving alkynylated 2-iodoanisoles and molecular iodine in the presence of sodium bicarbonate was developed and diiodo-functionalized benzo[b] furans were obtained in yields from ...

    • Synthesis of Lapachone Derivates via Ionic Liquid-Mediated Tandem Knoevenagel/Diels-Alder Reaction 

      Prado, Karinne E.; Name, Luccas L.; Oliveira, Rayssa P.; Guadagnin, Rafael C. [UNIFESP]; Pimenta, Daniel C.; Pena, Jesus M.; Cella, Rodrigo (Wiley-V C H Verlag Gmbh, 2017)
      The use of ionic liquid (IL) in Tandem Knoevenagel/Diels-Alder Reaction is an optimization method for one-pot procedures, providing great results under mild conditions. In this paper, four new Lapachone derivatives were ...

    • Synthesis of silver nanoparticles using agar-agar water solution and femtosecond pulse laser irradiation 

      Matos, Ricardo Almeida de [UNIFESP]; Cordeiro, Thiago da Silva; Samad, Ricardo Elgul; Sicchieri, Leticia Bonfante; Vieira Junior, Nilson Dias; Courrol, Lilia Coronato [UNIFESP] (Elsevier B.V., 2013-04-20)
      We report a method to synthetize silver nanoparticles using an agar-agar solution illuminated by light from a xenon lamp, followed by irradiation by ultrashort laser pulses. Spherical nanoparticles of similar to 100 nm ...

    • Synthesis of Silylbiaryl Triflates by Chemoselective Suzuki Reaction 

      Moreira, Barbara V. [UNIFESP]; Muraca, Ana Carolina A. [UNIFESP]; Raminelli, Cristiano [UNIFESP] (Georg Thieme Verlag Kg, 2017)
      A modular approach for the synthesis of functionalized silylbiaryl triflates has been developed. Iodinated silylaryl triflates were prepared via a gram-scale diiodination reaction, followed by a one-flask transformation, ...

    • Synthesis, characterization and catalytic evaluation of cubic ordered mesoporous iron-silicon oxides 

      Martins, T. S. [UNIFESP]; Mahmoud, A.; Cides da Silva, L. C.; Cosentino, I. C.; Tabacniks, M. H.; Matos, J. R.; Freire, R. S.; Fantini, M. C. A. (Elsevier B.V., 2010-11-01)
      Iron was successfully incorporated in FDU-1 type cubic ordered mesoporous silica by a simple direct synthesis route. the (Fe/FDU-1) samples were characterized by Rutherford back-scattering spectrometry (RBS), small angle ...

    • Synthesis, characterization and cytotoxicity of glutathione- and PEG-glutathione-superparamagnetic iron oxide nanoparticles for nitric oxide delivery 

      Santos, M. C. [UNIFESP]; Seabra, A. B. [UNIFESP]; Pelegrino, M. T. [UNIFESP]; Haddad, P. S. [UNIFESP] (Elsevier Science Bv, 2016)
      Superparamagnetic iron oxide nanoparticles (SPIONs), with appropriate surface coatings, are commonly used for biomedical applications, such as drug delivery. For the successful application of SPIONs, it is necessary that ...

    • Synthesis, characterization, and cytotoxicity of glutathione-PEG-iron oxide magnetic nanoparticles 

      Haddad, Paula Silvia [UNIFESP]; Santos, Marconi da Cruz [UNIFESP]; de Guzzi Cassago, Carolina Aparecida; Bernardes, Juliana S.; de Jesus, Marcelo Bispo; Seabra, Amedea Barozzi [UNIFESP] (Springer, 2016)
      Recently, increasing interest is spent on the synthesis of superparamagnetic iron oxide nanoparticles, followed by their characterization and evaluation of cytotoxicity towards tumorigenic cell lines. In this work, magnetite ...

    • Targeting Cell Division Cycle 25 Homolog B To Regulate Influenza Virus Replication 

      Perwitasari, Olivia; Torrecilhas, Ana Claudia [UNIFESP]; Yan, Xiuzhen; Johnson, Scott; White, Caleb; Tompkins, S. Mark; Tripp, Ralph A. (Amer Soc Microbiology, 2013-12-01)
      Influenza virus is a worldwide global health concern causing seasonal morbidity mortality and economic burden. Chemotherapeutics is available; however, rapid emergence of drug-resistant influenza virus strains has reduced ...

    • Technical challenges of working with extracellular vesicles 

      Ramirez, Marcel Ivan; Amorim, Maria G.; Gadelha, Catarina; Milic, Ivana; Welsh, Joshua A.; Freitas, Vanessa Morais; Nawaz, Muhammad; Akbar, Naveed; Couch, Yvonne; Makin, Laura; Cooke, Fiona; Vettore, Andre Luiz [UNIFESP]; Xander, Patricia [UNIFESP]; Freezor, Roberta; Pezuk, Julia A.; Rosa-Fernandes, Livia; Carreira, Ana Claudia Oliveira; Devitt, Andrew; Jacobs, Laura; Silva, Israel T.; Coakley, Gillian; Nunes, Diana Noronha; Carter, Dave; Palmisano, Giuseppe; Dias-Neto, Emmanuel (Royal Soc Chemistry, 2018)
      Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with potential applications in diagnosis, prognosis and therapeutic guidance in most pathological conditions. These nano-sized particles ...

    • Teleocichla wajapi, a new species of cichlid from the rio Jari, Brazil, with comments on T. centrarchus Kullander, 1988 (Teleostei: Cichlidae) 

      Varella, Henrique Rosa; Moreira, Cristiano Rangel [UNIFESP] (Magnolia Press, 2013-04-23)
      Teleocichla wajapi, new species, is described from the rio Jari basin, northern Brazil. The new species differs from its congeners by possessing four anal-fin spines, 56-62 scales in E1 series, smaller orbital diameter ...

    • Tellurium in organic synthesis: a general approach to buteno- and butanolides 

      Ferrarini, Renan S.; Dos Santos, Alcindo A.; Comasseto, Joao V. [UNIFESP] (Elsevier B.V., 2012-12-23)
      The naturally occurring butanolides (-)-blastmycinolactol, (+)-blastmycinone, (-)-NFX-2, (+)-antimycinone as well as the four stereoisomers of the butenolide Acaterin were prepared in high enantiomeric purity using ...

    • Tellurium in organic synthesis: a general approach to buteno- and butanolides 

      Ferrarini, Renan S.; Dos Santos, Alcindo A.; Comasseto, Joao V. [UNIFESP] (Elsevier B.V., 2012-10-07)
      The naturally occurring butanolides (-)-blastmycinolactol, (+)-blastmycinone, (-)-NFX-2, (+)-anti-mycinone as well as the four stereoisomers of the butenolide Acaterin were prepared in high enantiomeric purity using ...

    • Temperamento dos adeptos do uso ritual da Ayahuasca do Centro Luz Divina, Piedade – SP, Brasil. 

      Fonseca, Arilton Martins [UNIFESP]; Rodrigues, Eliana [UNIFESP] (PUC-PR, 2021-09-17)
      O temperamento pode ser considerado a base do humor, do comportamento e da personalidade do indivíduo. Assim, o objetivo deste estudo foi verificar a influência do consumo ritual da Ayahuasca pelos adeptos daimistas do ...

    • Temporal partitioning of adaptive responses of the murine heart to fasting 

      Brewer, Rachel A.; Collins, Helen E.; Berry, Ryan D.; Brahma, Manoja K.; Tirado, Brian A.; Peliciari-Garcia, Rodrigo A. [UNIFESP]; Stanley, Haley L.; Wende, Adam R.; Taegtmeyer, Heinrich; Rajasekaran, Namakkal Soorappan; Darley-Usmar, Victor; Zhang, Jianhua; Frank, Stuart J.; Chatham, John C.; Young, Martin E. (Pergamon-Elsevier Science Ltd, 2018)
      Recent studies suggest that the time of day at which food is consumed dramatically influences clinically-relevant cardiometabolic parameters (e.g., adiposity, insulin sensitivity, and cardiac function). Meal feeding benefits ...

    • Terpenoids from Leaves of Guarea macrophylla Display In Vitro Cytotoxic Activity and Induce Apoptosis In Melanoma Cells 

      Conserva, Geanne Alexandra A. [UNIFESP]; Girola, Natalia [UNIFESP]; Figueiredo, Carlos R. [UNIFESP]; Azevedo, Ricardo A.; Mousdell, Sasha; Sartorelli, Patricia [UNIFESP]; Soares, Marisi G.; Antar, Guilherme M.; Lago, Joao Henrique G. (Georg Thieme Verlag Kg, 2017)
      Guarea macrophylla is a Brazilian plant species that has been used in folk medicine to treat a range of diseases. Our ongoing work focuses on the discovery of new bioactive natural products derived from Brazilian flora. ...

    • Tetraquark production in double parton scattering 

      Carvalho, F. [UNIFESP]; Cazaroto, E. R.; Goncalves, V. P.; Navarra, F. S. (Amer Physical Soc, 2016)
      We develop a model to study tetraquark production in hadronic collisions. We focus on double parton scattering and formulate a version of the color evaporation model for the production of the X(3872) and of the T-4c ...