Now showing items 557-576 of 1033

    • IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2(V617F)-positive myeloproliferative neoplasms 

      Campos, Paula de Melo; Machado-Neto, Joao A.; Eide, Christopher A.; Savage, Samantha L.; Scopim-Ribeiro, Renata; Souza Duarte, Adriana da Silva; Favaro, Patricia [UNIFESP]; Lorand-Metze, Irene; Costa, Fernando F.; Tognon, Cristina E.; Druker, Brian J.; Olalla Saad, Sara T.; Traina, Fabiola (Impact Journals Llc, 2016)
      The recurrent V617F mutation in JAK2 (JAK2(V617F)) has emerged as the primary contributor to the pathogenesis of myeloproliferative neoplasms (MPN). However, the lack of complete response in most patients treated with the ...

    • Is Lambda CDM an effective CCDM cosmologdy? 

      Lima, J. A. S.; Santos, R. C. [UNIFESP]; Cunha, J. V. (Iop Publishing Ltd, 2016)
      We show that a cosmology driven by gravitationally induced particle production of all non-relativistic species existing in the present Universe mimics exactly the observed flat accelerating Lambda CDM cosmology with just ...

    • Is the new resonance spin 0 or 2? Taking a step forward in the Higgs boson discovery 

      Alves, Alexandre (Amer Physical Soc, 2012-12-19)
      The observation of a new boson of mass similar to 125 GeV at the CERN LHC may finally have revealed the existence of a Higgs boson. Now we have the opportunity to scrutinize its properties, determining its quantum numbers ...

    • Is There Association between Vitamin D Concentrations and Body Mass Index Variation in Women Submitted to Y-Roux Surgery? 

      dos Santos, Maria Tereza A.; Suano-Souza, Fabiola Isabel [UNIFESP]; Affonso Fonseca, Fernando Luiz [UNIFESP]; Lazaretti-Castro, Marise [UNIFESP]; Saccardo Sarni, Roseli Oselka [UNIFESP] (Hindawi Ltd, 2018)
      Objective. To evaluate vitamin D deficiency and body composition of women submitted to bariatric surgery and relate their body mass index variation after surgery to 25(OH) D concentrations. Method. A cross-sectional and ...

    • Isolation and purification of bromelain from waste peel of pineapple for therapeutic application 

      Bresolin, Iara Rocha Antunes Pereira [UNIFESP]; Bresolin, Igor Tadeu Lazzarotto [UNIFESP]; Silveira, Edgar; Tambourgi, Elias Basile; Mazzola, Priscila Gava (Instituto de Tecnologia do Paraná - Tecpar, 2013-12-01)
      The aim of this work was to isolate and purify bromelain extracted from the pineapple peel by ammonium sulfate precipitation (40-80%), followed by desalting and freeze-drying with a 75% activity recovery and 2.2 fold ...

    • Isolation determines patterns of species presence in highly fragmented landscapes 

      Boscolo, Danilo [UNIFESP]; Metzger, Jean Paul (Wiley-Blackwell, 2011-12-01)
      In fragmented landscapes, changes in habitat availability, patch size, shape and isolation may affect survival of local populations. Proposing efficient conservation strategies for such species relies initially on ...

    • Jacaranone Induces Apoptosis in Melanoma Cells via ROS-Mediated Downregulation of Akt and p38 MAPK Activation and Displays Antitumor Activity in Vivo 

      Massaoka, Mariana Hiromi [UNIFESP]; Matsuo, Alisson Leonardo [UNIFESP]; Figueiredo, Carlos Rogerio [UNIFESP]; Farias, Camyla F. [UNIFESP]; Girola, Natalia [UNIFESP]; Arruda, Denise Costa [UNIFESP]; Scutti, Jorge Augusto Borin [UNIFESP]; Romoff, Paulete; Favero, Oriana A.; Ferreira, Marcelo J. P.; Lago, Joao Henrique Ghilardi [UNIFESP]; Travassos, Luiz Rodolpho [UNIFESP] (Public Library Science, 2012-06-06)
      Background: Malignant melanoma is a deadly type of metastatic skin cancer with increased incidence over the past 30 years. Despite the advanced knowledge on the biology, immunobiology and molecular genetics of melanoma, ...

    • Jacobsen's catalyst interaction with polydimethylsiloxane/tetraethoxysilane network and solvent molecules: Theoretical design of a new polymeric membrane 

      Pliego, Josefredo R. [UNIFESP]; Schiavon, Marco A. (Amer Chemical Soc, 2008-09-25)
      Theoretical calculations were used for understanding the occlusion of the Jacobsen's catalyst inside a polydimethylsiloxane/tetraethoxysilane (PDMS/TEOS) polymeric membrane. Our analysis indicates there is a partition ...

    • Janus emulsions of bixa orellana oil 

      Leonardi, Gislaine Ricci; Silva, Marina Martines [UNIFESP]; Guimaraes, Carina Moreira [UNIFESP]; Perrechil, Fabiana de Assis [UNIFESP]; Friberg, Stig (Taylor & francis inc, 2016)
      Janus emulsions of the oil from the Bixa orellana (BO) nut, silicone oil (SO), and an aqueous solution of Tween 80 were prepared by intense mixing and optical microscopy images were obtained of the drops. The results showed ...

    • Jets plus same-sign dileptons signatures from fermionic leptoquarks at the LHC 

      Alves, Alexandre [UNIFESP]; Ramirez Barreto, E.; Dias, A. G. (Amer Physical Soc, 2012-09-24)
      Within the 3-3-1 model framework, we consider the production and decay of fermionic leptoquarks into a striking experimental signature at the LHC: a narrow resonance at the b jet plus same-sign dileptons channel. the data ...

    • Karyotype characterization and nucleolar organizer regions of marsupial species (Didelphidae) from areas of Cerrado and Atlantic Forest in Brazil 

      Pereira, Nubia P.; Ventura, Karen; Silva Junior, Magno C.; Melo e Silva, Daniela de; Yonenaga-Yassuda, Yatiyo; Pellegrino, Katia Cristina Machado [UNIFESP] (Soc Brasil Genetica, 2008-01-01)
      The karyotypes of 23 specimens belonging to 16 species from nine genera of Brazilian marsupials (family Didelphidae) were studied. The animals were collected in eight localities of Cerrado or Atlantic Forest biomes in the ...

    • Karyotype plasticity in crickets: Numerical, morphological, and nucleolar organizer region distribution pattern of Anurogryllus sp. 

      Schneider, Marielle Cristina [UNIFESP]; Zacaro, Adilson Ariza; Ferreira, Amilton; Cella, Doralice Maria (Univ Arizona, 2010-07-02)
      Within the Orthopteran species, those of the suborder Ensifera have been rarely studied from the cytogenetic point of view, mainly due to the difficulties for taxonomic identification of its species. The Gryllidae is the ...

    • Karyotypes of a Cryptic Diploid Form of the Unisexual Leposoma percarinatum (Squamata, Gymnophthalmidae) and the Bisexual Leposoma ferreirai from the Lower Rio Negro, Amazonian Brazil 

      Laguna, Marcia M.; Rodrigues, Miguel T.; Santos, Rodrigo M. L. dos; Yonenaga-Yassuda, Yatiyo; Avila-Pires, Teresa C. S.; Hoogmoed, Marinus S.; Pellegrino, Katia C. M. [UNIFESP] (Soc Study Amphibians Reptiles, 2010-03-01)
      Karyotypes of Leposoma show a clear differentiation between species of the scincoides group from Brazilian Atlantic Forest (2n = 52, without distinctive size groups of chromosomes) and those of the parietale group from the ...

    • Kinetic Modeling of Ethanol Production by Scheffersomyces stipitis from Xylose 

      Farias, Daniele; Andrade, Rafael R. de [UNIFESP]; Maugeri-Filho, Francisco (Humana Press Inc, 2014-01-01)
      This work focuses on the kinetics of ethanol production by Scheffersomyces stipitis on xylose with the development of a mathematical model considering the effect of substrate and product concentrations on growth rate. ...

    • Kinetics of bainite precipitation in the Cu69.3Al18.8Mn10.3Ag1.6 alloy 

      Motta, M. B. J. L. [UNIFESP]; Adorno, A. T.; Santos, C. M. A.; Silva, R. A. G. [UNIFESP] (Elsevier Science Sa, 2017)
      In this work the kinetics of bainite precipitation in the Cu69.3Al18.8Mn10.3Ag1.6 alloy was studied using measurements of microhardness change with aging time, scanning electron microscopy (SEM), energy dispersive X-ray ...

    • Kinin B1 receptor gene ablation affects hypothalamic CART production 

      Torres, Hugo A. M. [UNIFESP]; Motta, Fabiana Louise [UNIFESP]; Sales, Vicencia Micheline [UNIFESP]; Batista, Carolina [UNIFESP]; Silva, Joelcimar M. da; Vignoli, Thiago [UNIFESP]; Barnabe, Gabriela F. [UNIFESP]; Goeldner, Francine O. [UNIFESP]; D'Almeida, Vania [UNIFESP]; Bittencourt, Jackson C.; Sinigaglia-Coimbra, Rita [UNIFESP]; Bader, Michael; Mello, Luiz Eugenio A. M. [UNIFESP]; Pesquero, Joao Bosco [UNIFESP] (Walter de Gruyter Gmbh, 2013-07-01)
      A role for the kinin B1 receptor in energy-homeostatic processes was implicated in previous studies; notably, the studies where kinin B1 receptor knockout mice (B1(-/-)) were shown to have impaired adiposity, impaired ...

    • L-arginine in the ischemic phase protects against liver ischemia-reperfusion injury 

      Taha, Murched Omar [UNIFESP]; Caricati-Neto, Afonso [UNIFESP]; Miranda-Ferreira, Regiane [UNIFESP]; Simões, Manuel de Jesus [UNIFESP]; Monteiro, Hugo Pequeno [UNIFESP]; Fagundes, Djalma José [UNIFESP] (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2012-09-01)
      PURPOSE: To investigate the effects of intravenous L-arginine (LG) infusion on liver morphology, function and proinflammatory response of cytokines during the early phase of ischemia-reperfusion injury (IRI). METHODS: ...

    • Lack of agreement between objective and subjective measures in the evaluation of masticatory function: A preliminary study 

      Pedroni-Pereira, Aline; Salome Marquezin, Maria Carolina [UNIFESP]; Araujo, Darlle Santos; Pereira, Luciano Jose; Bommarito, Silvana [UNIFESP]; Castelo, Paula Midori [UNIFESP] (Pergamon-Elsevier Science Ltd, 2018)
      The evaluation of mastication is important to understand the masticatory behavior and diagnose feeding difficulties. The objective of this preliminary study was to verify if there is agreement between objective and subjective ...

    • Landscape indicators of the success of protected areas on habitat recovery for the Golden Lion Tamarin (Leontopithecus rosalia) 

      Valle, Ivana Cola; Francelino, Marcio Rocha; Hardt, Elisa [UNIFESP]; Koenow Pinheiro, Helena Saraiva (Taylor & Francis Inc, 2018)
      Since 1974, conservation efforts to protect an endangered species, the Golden Lion Tamarin (GLT), have led to the creation of the first strict nature reserve in Brazil - the Poco das Antas Biological Reserve (REBIO) - and ...

    • Langmuir and Langmuir-Blodgett films of a quinoline-fluorene based copolymer 

      Correia, Fabio Conte; Wang, Shu H.; Peres, Laura O. [UNIFESP]; Caseli, Luciano [UNIFESP] (Elsevier B.V., 2012-01-20)
      The fabrication of Langmuir-Blodgett (LB) films of synthetic polymers allows the control of molecular architecture in order to optimize physical properties. in this paper, the surface chemistry of a quinoline-fluorene based ...