• Associação entre doses elevadas de ácido fólico com ativação de linfócitos T, B e NK e suas possíveis consequências no processo inflamatório em indivíduos saudáveis 

  Lucena, Maylla Rodrigues [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-12-19)

  BACKGROUND:Folate is a B-complex vitamin withanimportantrole on cell replication since its involvement in DNA and RNA synthesis. In Brazil, most pharmaceutical formulationsof folic acid (FA) taken by women who intend to ...

• Associação entre os alelos HLA-DRB1 e a aloimunização eritrocitária 

  Souza, Conceicao Pinheiro De [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-02-13)

  Background: The immunogenicity of antigens from blood group systems is now better understood by the availability of knowledge of the genetic basis of the proteins involved, molecular orientation in the erythrocyte membrane ...

• Análise dos alelos variantes de RHD e RHCE em pacientes aloimunizados e doadores de sangue com expressão alterada do antígeno RhD 

  Silva, Thamy Caroline De Souza [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-01-31)

  Background: The Rh system is considered the largest and most polymorphic blood group system, consisting of more than 50 antigens. The existence of a large number of RH alleles results in variant phenotypes that often ...

• Avaliação do papel da obesidade e de adipocinas como fatores de risco de Tromboembolismo Venoso: um estudo de casocontrole 

  Pinheiro, Patricia Nunes Bezerra [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-03-18)

  Introduction: The venous thromboembolism (VTE) is a frequent disease related to a relevant morbimortality. The association between obesity and VTE is particularly important due the increased prevalence of obesity in the ...

• Impacto do estado nutricional nos desfechos clínicos de pacientes submetidos a transplante alogênico de células progenitoras hematopoéticas 

  Hirose, Erika Yuri [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-01-31)

  Background: Malnutrition is a common finding in allogeneic hematopoietic stem cell transplantation (alloHSCT) patients, and its influence on transplant outcomes is uncertain, with conflicting results. Objetive: This study ...

• Avaliação da função renal em pacientes com Anemia Falciforme 

  Cruz, Sonia Maria Pereira [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-04-25)

  In the last decades, it has been observed an improvement in survival of sickle cell disease (SCD) patients. Pursuant that, the diagnosis of sickle cell nephropathy has significantly increased and chronic renal disease ...

• Características clínico-laboratoriais, análise mutacional do gene PIG-A e perfil metabolômico em pacientes com hemoglobinúria paroxística noturna 

  Yamakawa, Patricia Eiko [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-04-18)

  Introduction: Paroxysmal nocturnal hemoglobinuria (PNH) is a disorder due to an acquired abnormality in the phosphatidylinositol glycan class A (PIG-A) gene. This leads to partial or complete absence of all GPI-linked ...

• Análise da contribuição do inflamassoma na heterogeneidade clínica de pacientes com doença falciforme 

  Dutra, Valeria De Freitas [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-11-21)

  In spite of having a molecular basis, Sickle cell disease (SCD) is an inflammatory state with abnormal cell activation. Physiopathological factors are not completely understood, but it is known that interleukins plays an ...

• Importância do gene WEE1 e efeitos da sua inibição na sobrevida de células-tronco tumorais do Mieloma Múltiplo 

  Dantas, Rebecca Silveira Santos Barbosa [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-09-26)

  Introduction: Multiple myeloma (MM) is characterized by the infiltration of tumor plasmacytes into the bone marrow (BM), synthesis and secretion of monoclonal immunoglobulins and tissue damage. The presence of cancer stem ...

• Correlação entre níveis séricos de 25-hidroxivitamina D, desenvolvimento de Dech e avaliação do estado nutricional em pacientes submetidos ao transplante alogênico de células-tronco hematopoiéticas 

  Barban, Juliana Bernardo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-02-28)

  Objectives: Verify the prevalence of Vitamin D (VD) deficiency in patients submitted to Hematopoietic Stem Cell Transplantation (TCTH) before and after implementing the VD protocol. Check the 25-hydroxyvitamin D [25 (OH) ...

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