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Effects of paradoxical sleep deprivation on genital reflexes in five rat strains
(Elsevier B.V., 2006-02-01)
This study examined the effects of cocaine on genital reflexes in paradoxical sleep-deprived (PSD) male rats of five strains since it has been demonstrated that this drug enhances genital reflexes in Wistar PSD rats. At ...
Distinct effects of paradoxical sleep deprivation and cocaine administration on sexual behavior in male rats
(Carfax Publishing, 2002-04-01)
As there are data showing enhanced sexual activity in paradoxical sleep deprived (PSD) rats, and cocaine (COC) is a drug of abuse known to also increase the sexual drive, the present study aimed to assess sexual behavior ...
Sleep disordered breathing in Parkinson's disease: A critical appraisal
(W B Saunders Co Ltd, 2014-04-01)
Parkinson's disease (PD) is the second most common neurodegenerative disorder, characterized by resting tremor, rigidity, bradykinesia and postural instability, and is associated with non-motor features, including sleep ...
Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE)
(Wiley-Blackwell, 2014-05-01)
ObjectiveThimet oligopeptidase (TOP) is a metalloprotease that has been associated with peptide processing in several nervous system structures, and its substrates include several peptides such as bradykinin, amyloid beta ...
The reciprocal interaction between sleep and type 2 diabetes mellitus: facts and perspectives
(Associação Brasileira de Divulgação Científica, 2008-03-01)
Type 2 diabetes mellitus is a systemic disease characterized by intolerance to glucose and peripheral resistance to insulin. This endocrine disease affects fundamental mechanisms of the central nervous system and jeopardizes ...
Effects of sleep deprivation during pregnancy on the reproductive capability of the offspring
(Elsevier B.V., 2013-12-01)
Objective: To investigate the effects of sleep deprivation during pregnancy on the reproductive capability of the offspring.Design: Using a sleep loss model or control home-cage group (male and females rats) to evaluate ...
Sex differences in sleep pattern of rats in an experimental model of osteoarthritis
(Elsevier B.V., 2011-07-01)
Background: Osteoarthritis (OA) is a major healthcare burden with increasing incidence, and is characterised by the degeneration of articular cartilage. OA is associated with chronic pain and sleep disturbance.Objective: ...
Paradoxical sleep deprivation impairs acquisition, consolidation, and retrieval of a discriminative avoidance task in rats
(Elsevier B.V., 2008-11-01)
The aim of the present study was to investigate the effects of paradoxical sleep deprivation (PSD) for 96 h on the learning/memory processes in rats submitted to the plus-maze discriminative avoidance task (PMDAT). which ...
Acute systemic blockade of D2 receptors does not accelerate the extinction of cocaine-associated place preference
(Elsevier B.V., 2009-12-04)
Facilitation of extinction can be used as a therapeutic tool in treatment of both post-traumatic stress disorder and drug addiction. the present study examined whether the blockade of D2 receptors before each extinction ...
Exercise training improves sleep pattern and metabolic profile in elderly people in a time-dependent manner
(Biomed Central Ltd, 2011-07-06)
Aging and physical inactivity are two factors that favors the development of cardiovascular disease, metabolic syndrome, obesity, diabetes, and sleep dysfunction. in contrast, the adoption a habitual of moderate exercise ...