Now showing items 1-10 of 67
Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review
(Springer Wien, 2017)
The objective of this study was to evaluate whether Vitex agnus castus is a safe and effective treatment for PMS and premenstrual dysphoric disorder (PMDD) and to discuss the implications of these findings for clinical ...
Early intervention in psychosis: a map of clinical and research initiatives in Latin America
(Associação Brasileira de Psiquiatria - ABP, 2011-10-01)
OBJECTIVE: This article aims to review Latin America's early intervention services in psychosis and to shed light into their challenges and particularities. METHOD: An internet-based search comprising medical societies' ...
The paradigm of premature aging in bipolar disorder
Inter-relation between brain-derived neurotrophic factor and antioxidant enzymes in bipolar disorder
Objectives: Accumulating evidence indicates that oxidative stress and neurotrophins have a bidirectional relationship. In this post hoc, exploratory analysis, we investigated the association between plasma brain-derived ...
Analytical approaches for lipidomics and its potential applications in neuropsychiatric disorders
(Taylor & Francis Ltd, 2017)
Objectives: In this review, the authors discuss an overview of lipidomics followed by in-depth discussion of its application to the study of human diseases, including extraction methods of lipids, analytical techniques and ...
Evaluation of neurotransmitter receptor gene expression identifies GABA receptor changes: A follow-up study in antipsychotic-naive patients with first-episode psychosis
(Elsevier B.V., 2014-09-01)
A study of the gene expression levels in the blood of individuals with schizophrenia in the beginning of the disease, such as first-episode psychosis (FEP), is useful to detect gene expression changes in this disorder in ...
Impact of inequalities in health care on the mortality risk of individuals with severe mental illnesses
(Assoc Brasileira Psiquiatria, 2017)
Neuroinflammation and glial cell activation in mental disorders
Mental disorders (MDs) are highly prevalent and potentially debilitating complex disorders which causes remain elusive. Looking into deeper aspects of etiology or pathophysiology underlying these diseases would be highly ...
Treatment with a GLP-1R agonist over four weeks promotes weight loss-moderated changes in frontal-striatal brain structures in individuals with mood disorders
(Elsevier Science Bv, 2017)
Cognitive deficits are a core feature across psychiatric disorders. Emerging evidence indicates that metabolic pathways are highly relevant for the substrates and phenomenology of the cognitive domain. Herein, we aimed to ...
Impact of childhood stress on psychopathology
(Associação Brasileira de Psiquiatria - ABP, 2012-12-01)
OBJECTIVE: Advances in our knowledge of mental disorder (MD) genetics have contributed to a better understanding of their pathophysiology. Nonetheless, several questions and doubts persist. Recent studies have focused on ...