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Síntese e caracterização espectroscópica de compostos de coordenação contendo o ligante dipirido [3,2-f: 2,3-h] quinoxalina 2,3 ditetrazol
(Universidade Federal de São Paulo, 2016-12-19)
The work had two main lines: an experimental and a computacional one. The experimental work comprehended: synthesis of the liganddipirido [3,2-f: 2?,3?-h] quinoxalina ? 2,3 ditetrazol(dpq-dTzol), synthesis of coordination ...
Preparação e caracterização de derivados da 8-hidroxiquinolina e avaliação de suas atividades leishmanicidas utilizando a espécie Leishmania (Leishmania) amazonensis
(Universidade Federal de São Paulo, 2016-10-19)
Quinoline core is present in several biologically active substances. According to the literature 8-hydroxyquinoline has presented significant leishmanicidal activity against promastigote and amastigote forms of three species ...
Avaliação da atividade herbicida e citotóxica de produtos naturais de Pluchea sagitallis (asteraceae) e seus derivados sintéticos
(Universidade Federal de São Paulo, 2016-07-06)
In this proposal, the herbicide potential of the substances isolated from extracts of the roots of Pluchea sagittalis (Asteraceae) has been studied, a species collected in the area of the copper department of Mina do ...
Degradação da amoxicilina em efluentes simulados da indústria farmacêutica via processos oxidativos avançados
(Universidade Federal de São Paulo, 2016-01-29)
Among the emerging pollutants, drugs, particularly antibiotics, have attracted great attention. This is due to the high consumption in human and veterinary medicine, the potential of causing toxicity to living organisms ...
Processos oxidativos avançados aplicados no tratamento de águas de lavagem da indústria farmacêutica
(Universidade Federal de São Paulo, 2016-07-26)
The pharmaceutical residues are an emergent class of environmental contaminants extensively used in human and veterinary medicine. The main waste entry route into the environment is the dumping of domestic sewage, treated ...
Desenvolvimento de potenciais agentes leishmanicidas: benzotiazois inibidores de N-miristoiltransferase
(Universidade Federal de São Paulo, 2016-06-17)
N-myristoyltransferase is an enzyme responsible for anchoring proteins to the plasma mem- brane through a cotranslational mechanism of lipidation of proteins in eukaryotes. Previous studies have shown the benzothiazolic ...
Desenvolvimento de sílicas mesoporosas para a liberação controlada e prolongada de fármacos
(Universidade Federal de São Paulo, 2016-02-05)
Ordered mesoporous silicas has been considered one of the most promising inorganic systems to transport and control / sustain the release of drugs aiming to provide enhanced efficiency and reduced side effects in treatments ...
Desenvolvimento de métodos analíticos alternativos para microcistinas através da derivatização com probes ópticos
(Universidade Federal de São Paulo, 2016-01-07)
The cyanobacteria inhabit different ecosystems and have substantial economic and ecological importance. However, they are a matter of concern when there is a massive growth of these organisms. Some secondary metabolites ...
Estudo da termodifusão e efeitos fototérmicos em nanopartículas metálicas e bimetálicas
(Universidade Federal de São Paulo, 2016-11-11)
In this work, iron oxide nanoparticles (NPs) coated with several ligands and bimetallic NPs (Fe and Au) were produced following three methodologies: co-precipitation of iron salts, thermal decomposition of coordination ...
Estudo óptico conformacional de arilamidas e S-nitrosotióis derivados de SNAP
(Universidade Federal de São Paulo, 2016-04-11)
Nitric oxide is a versatile molecule that can be found both in the atmosphere, as in many organisms. Studies have revealed its varied functions, for example, antiplatelet and vasodilatory actions. This study aimed to ...