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Epidemiologia molecular de isolados clínicos de Klebsiella pneumoniae produtores de KPC-2 Provenientes da cidade de Juiz De Fora - MG
(Universidade Federal de São Paulo, 2017-11-22)
This study aimed at the molecular characterization of clinical isolates of Klebsiella pneumoniae that showed resistance to carbapenems obtained from urine samples from 2009 to 2014, in a private laboratory in Juiz de Fora ...
Desenvolvimento de minicomprimidos veiculando papaína livre e complexada com ciclodextrinas para a liberação imediata.
(Universidade Federal de São Paulo, 2018-08-23)
Papain is a proteolytic enzyme widely used in the treatment of wounds and has recently shown potential activity in promoting the absorption of drugs in the gastrointestinal tract. Solid dosage forms are an interesting ...
Análise da expressão dos genes ompF e RecA em Escherichia coli exposta a antimicrobianos e docking molecular para inibidores da recA
(Universidade Federal de São Paulo, 2018-12-12)
Some antimicrobial agents, such as ciprofloxacin (CIP), can lead to genetic changes in Escherichia coli by inducing the SOS Response, process in which RecA protein plays an essencial role. In sub-inhibitory concentrations ...
Avaliação da microextração líquid-líquido dispersiva na determinação de impurezas metálicas em Arnica
(Universidade Federal de São Paulo (UNIFESP), 2020-07-24)
Arnicas Solidago microglossa DC. and Arnica montana L.Arnica, are a natural medicine with analgesic, anti-inflammatory and antiseptic action, is easily accessible by the Brazilian population. These products are susceptible ...
Avaliação dos efeitos de vesículas extracelulares produzidas por L. (L.) Amazonensis sobre células B-1 e macrófagos Murinos
(Universidade Federal de São Paulo, 2017-06-27)
Leishmaniasis is a group of diseases caused by protozoa belonging to the genus Leishmania. In mammalian hosts, the parasite is able to infect and proliferate within various types of cells such as tissue macrophages and B-1 ...
Avaliação de peptídeos sintéticos selecionados por phage display para o sorodiagnóstico da Paracoccidioidomicose
(Universidade Federal de São Paulo, 2017-06-29)
Paraccocidioidomycosis (PCM) is a systemic granulomatous disease caused by the thermo-dimorphic fungus from complex Paraccocidioides. The disease diagnosis uses both direct detection of the fungus in biological samples and ...
Síntese e avaliação de derivados do LINS01003 potencialmente ligantes de receptores histaminérgicos H4
(Universidade Federal de São Paulo, 2017-03-27)
Histamine is an important chemical mediator of the organism and is related to several physiological and pathological conditions, its effects produced through interactions with histaminergic G protein coupled receptors ...
Desenvolvimento e caracterização de scaffolds porosos de quitosana visando aplicações biomédicas
(Universidade Federal de São Paulo (UNIFESP), 2019-03-28)
The development of scaffolds, obtained from biodegradable materials, is a point of great interest in tissue bioengineering. A bioactive material is considered a cell biocondutor when it acts as a temporary fill element ...
Obtenção e estudo fitoquímico do extrato hidroglicólico de Mouriri Elliptica Martius (Melastomataceae), aplicação em formulação fotoprotetora e avaliação in vitro do FPS
(Universidade Federal de São Paulo, 2018-12-07)
Nowadays life expactancy is increasing and with it the skin ages. A loss of function and differences in skin appearance proceed unavoidably. Exposure to UV radiation can induce cellular changes in skin cells, resulting in ...
Síntese de análogos da nifuroxazida potencialmente inibidores da via JAK-STAT
(Universidade Federal de São Paulo, 2019-12-13)
JAK-like proteins are involved in the transmission of information from the extracellular medium to the nucleus by phosphorylating cytoplasmic peptides known as STAT, which dimerize and thereby migrate to the nucleus by ...