Browsing PPG - Ciências Farmacêuticas by Submit Date
Now showing items 1-20 of 75
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Implementação da atenção Farmacêutica no SUS: um estudo de caso
(Universidade Federal de São Paulo, 2017-09-27) -
Endotélio venoso: estabelecimento e caracterização de culturas primárias e a produção de fatores derivados do endotélio de veia cava e veia porta de ratos
(Universidade Federal de São Paulo, 2017-03-17)The endothelial cell plays an essential role in vascular control by the release of Endothelium- Derived Relaxing Factors (EDRFs) [nitric oxide (NO), prostacyclin (PGI2) and endotheliumderived hyperpolarizing factor (EDHF)], ...
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Desenvolvimento farmacotécnico e validação analítica de comprimidos revestidos gastrorresistentes a partir do extrato padronizado de Harpagophytum procumbens DC
(Universidade Federal de São Paulo, 2017-03-24)The project aimed to develop a traditional herbal medicine from the dry extract, standardized in harpagoside, from the secondary roots of the plant species Harpagophytum procumbens DC. (Pedaliaceae), popularly known as ...
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Desenvolvimento farmacotécnico e validação analítica de comprimidos revestidos a partir do extrato padronizado de Actaea racemosa L.
(Universidade Federal de São Paulo, 2017-03-24)The project aims to develop an herbal medicine from the dry extract, standardized in 23-epi-26-desoxiactein, from the roots of the plant species Actaea racemosa L. (Ranunculaceae), popularly known as "black cohosh". The ...
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Avaliação dos efeitos de vesículas extracelulares produzidas por L. (L.) Amazonensis sobre células B-1 e macrófagos Murinos
(Universidade Federal de São Paulo, 2017-06-27)Leishmaniasis is a group of diseases caused by protozoa belonging to the genus Leishmania. In mammalian hosts, the parasite is able to infect and proliferate within various types of cells such as tissue macrophages and B-1 ...
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Avaliação de peptídeos sintéticos selecionados por phage display para o sorodiagnóstico da Paracoccidioidomicose
(Universidade Federal de São Paulo, 2017-06-29)Paraccocidioidomycosis (PCM) is a systemic granulomatous disease caused by the thermo-dimorphic fungus from complex Paraccocidioides. The disease diagnosis uses both direct detection of the fungus in biological samples and ...
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Crio laser forese utilizado como um método biofísico na promoção da penetração cutânea da cafeína
(Universidade Federal de São Paulo, 2017-06-26)The main barrier to topical treatment systems is related to the ability of the active substance to pass through the stratum corneum. Thus, studies on penetration promoters have intensified. The objective of this work was ...
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Síntese e avaliação de derivados do LINS01003 potencialmente ligantes de receptores histaminérgicos H4
(Universidade Federal de São Paulo, 2017-03-27)Histamine is an important chemical mediator of the organism and is related to several physiological and pathological conditions, its effects produced through interactions with histaminergic G protein coupled receptors ...
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Utilização de ácido elágico e derivados como marcadores para a validação química de Mouriri elliptica Martius como insumo farmacêutico ativo vegetal
(Universidade Federal de São Paulo, 2017-07-07)Validated by folk medicine in ulcers and gastritis treatment, the “croadinha” (Mouriri elliptica) leaves are use as tea. This therapeutic action and it´s efficacy and safety was confirmed by preliminary studies highlighting ...
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Obtenção e caracterização de pró-fármacos derivados de terpenos de origem vegetal com potencial atividade antichagásica
(Universidade Federal de São Paulo, 2017-03-28)Current chemotherapy alternative directed to the treatment of Leishmaniasis and Chagas disease shows to be inadequate because the existence of parasitic resistance to treatment, limited efficacy to certain stages of the ...
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A influência de ésteres emolientes na percepção do consumidor e nas características sensoriais, físico-químicas e biometrológicas quando veiculados em emulsões corporais
(Universidade Federal de São Paulo, 2017-11-30)Lipophilic emollients such as esters may influence the sensory and physico-chemical characteristics of the cosmetic emulsions in which they are present. The objective of this work was to evaluate cosmetic emulsions produced ...
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Avaliação da segurança e eficácia "in vitro" da Cuscuta racemosa Martius
(Universidade Federal de São Paulo, 2017-07-04)Cuscuta racemosa, Mart is a parasitic plant belonging to the family Convolvulaceae, known in Brazil for the popular synonymy of "cipó chumbo" and "yarn of eggs". It is popularly used for its anti-inflammatory and healing ...
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Barra de cereais formulada com Plantas Alimentícias Não Convencionais (PANC) - yacon e ora-pro-nobis
(Universidade Federal de São Paulo, 2017-09-29)The present study had the objective of developing a cereal bar containing prebiotics and a higher quantity of protein and minerals, using two Non-Conventional Food Plants (PANCs): the ora-pro-nobis (Pereskia aculeata Mill) ...
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Desenvolvimento de nanopartículas lipídicas sólidas contendo filtro solar orgânico e óleo vegetal da flora brasileira
(Universidade Federal de São Paulo, 2017-06-23)The use of sunscreen products is widely promoted by schools, government agencies and health-related organizations to minimize sunburn and skin damage, which can lead to skin cancer. In this study, we developed stable solid ...
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Epidemiologia molecular de isolados clínicos de Klebsiella pneumoniae produtores de KPC-2 Provenientes da cidade de Juiz De Fora - MG
(Universidade Federal de São Paulo, 2017-11-22)This study aimed at the molecular characterization of clinical isolates of Klebsiella pneumoniae that showed resistance to carbapenems obtained from urine samples from 2009 to 2014, in a private laboratory in Juiz de Fora ...
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Estratégias analíticas para a obtenção de marcadores, validação e padronização de extratos de Gomphrena vaga Mart (Amaranthaceae)
(Universidade Federal de São Paulo, 2017-07-26)The species Gomphrena vaga Mart. presents an irregular distribution throughout the Brazilian territory, its name being a reference to such characteristic. It is part of the vegetation of forests and cerradões in the southeast ...
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Estudo da atividade da GTPaseRas de Paracoccidioides brasiliensis durante o termo-dimorfismo do fungo e após estresse induzido por espécies reativas de oxigênio e nitrogênio
(Universidade Federal de São Paulo, 2017-03-30)Paracoccidioides brasiliensis, a thermally dependent dimorphic fungus, is one of the etiological agents of paracoccidioidomycosis (PCM). The ability to evade the innate immune response of the host and cause disease is ...
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Implementação da Atenção Farmacêutica no SUS: um estudo de caso
(Universidade Federal de São Paulo, 2017-09-27)Introduction: Pharmaceutical care services have been recognized as a model of professional pharmaceutical practice allowing identification and intervention on drug-related problems, integrating drug users and staff as ...
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Participação das vesículas extracelulares de leveduras de Sporothrix brasiliensis na resposta imune da Esporotricose: estudo ex vivo e in vivo
(Universidade Federal de São Paulo, 2018-02-19)Sporotrichosis is a mycotic emerging infectious disease, it affects the skin, lymphatic system, and other organs from humans and animals. The fungus infection has a worldwide distribution and is endemic in areas from ...
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Síntese e avaliação da atividade de alquilfenóis substituídos em Trypanosoma cruzi
(Universidade Federal de São Paulo, 2018-03-28)In this work the natural products gibbilimbol A and B isolated from Piper malacophyllum were used as prototypes for the development of structural analogues given their promising anti-Trypanosoma cruzi activity and low ...