High prevalence of hepatitis E virus antibodies among blood donors in Southern Brazil

High prevalence of hepatitis E virus antibodies among blood donors in Southern Brazil

Author Passos-Castilho, Ana Maria Autor UNIFESP Google Scholar
de Sena, Anne Autor UNIFESP Google Scholar
Geraldo, Alexandre Google Scholar
Spada, Celso Google Scholar
Granato, Celso F. H. Autor UNIFESP Google Scholar
Abstract Brazil has been classified as moderately endemic for hepatitis E virus (HEV) infection. However, data on the seroprevalence of HEV in this region are limited. This study evaluated the prevalence of past or present HEV infection among blood donors in the metropolitan area of Itajai Valley, Southern Brazil, a region of predominant German heritage, where cultural habits result in a high consumption of pork. Serum samples from 300 blood donors were tested in December 2014 using serological and molecular methods. Anti-HEV IgG antibodies were detected in 30 (10%) subjects, and categorized age groups revealed an age-dependent increase of HEV seroprevalence. Only one subject had anti-HEV IgM, whereas none tested positive for HEV-RNA. The present data demonstrate a higher seroprevalence of anti-HEV IgG in blood donors than previously reported in Brazil. (c) 2015 Wiley Periodicals, Inc.
Keywords hepatitis E virus
blood donors
seroprevalence
Brazil
xmlui.dri2xhtml.METS-1.0.item-coverage Hoboken
Language English
Sponsor Fundacao de Amparo a Pesquisa do Estado de Sao Paulo
Grant number FAPESP: 2012/22925-3
FAPESP: 2013/03701-0
Date 2016
Published in Journal Of Medical Virology. Hoboken, v. 88, n. 2, p. 361-364, 2016.
ISSN 0146-6615 (Sherpa/Romeo, impact factor)
Publisher Wiley-Blackwell
Extent 361-364
Origin https://doi.org/10.1002/jmv.24336
Access rights Closed access
Type Article
Web of Science ID WOS:000368740500023
URI https://repositorio.unifesp.br/handle/11600/58643

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