Tramadol wound infiltration is not different from intravenous tramadol in children: a randomized controlled trial

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dc.contributor.author Giraldes, Ana Laura Albertoni [UNIFESP]
dc.contributor.author Sousa, Angela Maria
dc.contributor.author Slullitel, Alexandre
dc.contributor.author Guimaraes, Gabriel Magalhaes Nunes
dc.contributor.author Santos, Melina Genevieve Mary Egan
dc.contributor.author Pinto, Renata Evangelista
dc.contributor.author Ashmawi, Hazem Adel
dc.contributor.author Sakata, Rioko Kimiko [UNIFESP]
dc.date.accessioned 2020-11-03T14:40:35Z
dc.date.available 2020-11-03T14:40:35Z
dc.date.issued 2016
dc.identifier https://doi.org/10.1016/j.jclinane.2015.08.009
dc.identifier.citation Journal Of Clinical Anesthesia. New York, v. 28, p. 62-66, 2016.
dc.identifier.issn 0952-8180
dc.identifier.uri https://repositorio.unifesp.br/handle/11600/58628
dc.description.abstract Study Objective: The purpose of this trial was to assess if tramadol wound infiltration is superior to intravenous (IV) tramadol after minor surgical procedures in children because tramadol seems to have local anesthetic like effect. Design: Randomized double-blind controlled trial. Setting: Postanesthesia care unit. Patients: Forty children, American Society of Anesthesiologists physical status I or II, scheduled to elective inguinal hernia repair. Interventions: Children were randomly distributed in 1 of 2 groups: IV tramadol (group 1) or subcutaneous infiltration with tramadol (group 2). At the end of the surgery, group 1 received 2 mg/kg tramadol (3 mL) by IV route and 3-mL saline into the surgical wound; group 2 received 2 mg/kg tramadol (3 mL) into the surgical wound and 3-mL saline by IV route. Measurements: In the postanesthesia care unit, patients were evaluated for pain intensity, nausea and vomiting, time to first rescue medication, and total rescue morphine and dipyrone consumption. Main Results: Pain scores measured during the postanesthesia recovery time were similar between groups. Time to first rescue medication was shorter, but not statistically significant in the IV group. The total dose of rescue morphine and dipyrone was also similar between groups. Conclusions: We concluded that tramadol was effective in reducing postoperative pain in children, and there was no difference in pain intensity, nausea and vomiting, or somnolence regarding IV route or wound infiltration. (C) 2016 Elsevier Inc. All rights reserved. en
dc.format.extent 62-66
dc.language.iso eng
dc.publisher Elsevier Science Inc
dc.relation.ispartof Journal Of Clinical Anesthesia
dc.rights Acesso restrito
dc.subject Infiltration anesthesia en
dc.subject Tramadol en
dc.subject Intravenous administration en
dc.subject Postoperative pain en
dc.subject Hemioplasty en
dc.title Tramadol wound infiltration is not different from intravenous tramadol in children: a randomized controlled trial en
dc.type Artigo
dc.description.affiliation Univ Fed Sao Paulo, Pediat Anesthesia Unit, Dept Anesthesia, Div Surg, Sao Paulo, Brazil
dc.description.affiliation Canc Inst State Sao Paulo, Pain Management Serv, Sao Paulo, Brazil
dc.description.affiliation Santa Paula Hosp, Dept Anesthesia & Pain Management, Sao Paulo, Brazil
dc.description.affiliation Univ Sao Paulo, Univ Hosp, Dept Anesthesia, Sao Paulo, Brazil
dc.description.affiliation Univ Sao Paulo, Hosp Clin, Dept Anesthesia, Sao Paulo, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Pediat Anesthesia Unit, Dept Anesthesia, Div Surg, Sao Paulo, Brazil
dc.identifier.doi 10.1016/j.jclinane.2015.08.009
dc.description.source Web of Science
dc.identifier.wos WOS:000369194300013
dc.coverage New York
dc.citation.volume 28



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