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dc.contributor.authorGusso-Choueri, Paloma Kachel
dc.contributor.authorChoueri, Rodrigo Brasil [UNIFESP]
dc.contributor.authorSantos, Gustavo Souza
dc.contributor.authorde Araujo, Giuliana Seraphim
dc.contributor.authorFeitosa Cruz, Ana Carolina
dc.contributor.authorStremel, Tatiana
dc.contributor.authorde Campos, Sandro Xavier
dc.contributor.authorCestari, Marta Margarete
dc.contributor.authorOliveira Ribeiro, Ciro Alberto
dc.contributor.authorde Sousa Abessa, Denis Moledo
dc.identifier.citationMarine Pollution Bulletin. Oxford, v. 104, n. 43497, p. 229-239, 2016.
dc.description.abstractThe goal of the current study was to evaluate different genotoxicity tools in order to assess a marine protected area (MPA) affected by former mining activities and urban settlements. A catfish (Cathorops spixii) was analyzed for genotoxic effects at the (i) molecular and at the (ii) chromosomal levels. Through factor analysis, genotoxicity was found to be linked to levels of metals bioaccumulated and PAH metabolites in the bile. Micronucleus and nuclear alteration were less vulnerable to the effects of confounding factors in mildly contaminated areas since they were more frequently associated with bioaccumulated metals than the DNA analysis. The different genotoxicity responses allowed for the identification of sources of pollution in the MPA. This approach was important for detecting environmental risks related to genotoxic contaminants in a mildly contaminated MPA. (C) 2016 Elsevier Ltd. All rights reserved.en
dc.description.sponsorshipNational Council for Scientific and Technological Development (CNPq)
dc.description.sponsorshipSao Paulo Research Foundation (FAPESP)
dc.description.sponsorshipBrazilian Aquatic Research Foundation (FUNDESPA)
dc.description.sponsorshipBrazilian Commission for the Improvement of Higher Education Personnel in Brazil (CAPES)
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofMarine Pollution Bulletin
dc.rightsAcesso aberto
dc.subjectWeight of evidenceen
dc.subjectEnvironmental quality assessmenten
dc.subjectMultivariate approachen
dc.titleAssessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressorsen
dc.description.affiliationFed Univ Parana UFPR, Grad Program Ecol & Conservat, CP 19031, BR-81531990 Curitiba, Parana, Brazil
dc.description.affiliationFed Univ Parana UFPR, Dept Cellular Biol, Cellular Toxicol Lab, CP19031, BR-81531990 Curitiba, Parana, Brazil
dc.description.affiliationSao Paulo State Univ, Lab Study Aquat Pollut & Ecotoxicol NEPEA, Sao Vicente Campus UNESP Campus Litoral Paulista, BR-11330900 Sao Vicente, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Marine Sci, Santos Campus UNIFESP Santos, BR-11030490 Santos, SP, Brazil
dc.description.affiliationFed Univ Parana UFPR, Dept Genet, BR-81531990 Curitiba, Parana, Brazil
dc.description.affiliationUniv Sao Paulo IOUSP, Inst Oceanog, Praca Oceanog 191, BR-05508120 Sao Paulo, SP, Brazil
dc.description.affiliationUniv Estadual Ponta Grossa, Res Grp Environm & Sanit Analyt Chem QAAS, Av Gen Carlos Cavalcanti 4748, BR-84030900 Ponta Grossa, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Marine Sci, Santos Campus UNIFESP Santos, BR-11030490 Santos, SP, Brazil
dc.description.sponsorshipIDCNPq: 479899/2013-4
dc.description.sponsorshipIDFAPESP: 2009/52762-6
dc.description.sponsorshipIDCNPq: 308649/2011-7
dc.description.sponsorshipIDCNPq: 311609/2014-7
dc.description.sourceWeb of Science

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